N-[(1S,2S)-2-((S)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl)-2-methylsulfanyl-1-phenyl-ethyl]-2,4,6-trimethylbenzenesulfonamide

Base Information

Chemical Name:N-[(1S,2S)-2-((S)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl)-2-methylsulfanyl-1-phenyl-ethyl]-2,4,6-trimethylbenzenesulfonamide
CAS No.:345904-96-3
Molecular Formula:C₃₆H₄₀N₂O₄S₂
Molecular Weight:628.857
Hs Code.:

Synonyms:N-[(1S,2S)-2-((S)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl)-2-methylsulfanyl-1-phenyl-ethyl]-2,4,6-trimethylbenzenesulfonamide

Suppliers and Price of N-[(1S,2S)-2-((S)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl)-2-methylsulfanyl-1-phenyl-ethyl]-2,4,6-trimethylbenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[(1S,2S)-2-((S)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl)-2-methylsulfanyl-1-phenyl-ethyl]-2,4,6-trimethylbenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[(1S,2S)-2-((S)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl)-2-methylsulfanyl-1-phenyl-ethyl]-2,4,6-trimethylbenzenesulfonamide

There total 2 articles about N-[(1S,2S)-2-((S)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl)-2-methylsulfanyl-1-phenyl-ethyl]-2,4,6-trimethylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 148838-27-1
N-2,4,6-trimethylphenylsulfonylbenzaldimine

: 282550-72-5
(S)-4-isopropyl-3-methylsulfanylmethyl-5,5-diphenyl-oxazolidin-2-one

: 345904-96-3
N-[(1S,2S)-2-((S)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl)-2-methylsulfanyl-1-phenyl-ethyl]-2,4,6-trimethylbenzenesulfonamide

: N-[(1R,2S)-2-((S)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl)-2-methylsulfanyl-1-phenyl-ethyl]-2,4,6-trimethylbenzenesulfonamide

Guidance literature:: (S)-4-isopropyl-3-methylsulfanylmethyl-5,5-diphenyl-oxazolidin-2-one; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.0833333h;

N-2,4,6-trimethylphenylsulfonylbenzaldimine; In tetrahydrofuran; at -100 - -78 ℃; for 0.333333h; Further stages.;
DOI:10.1021/jo0155254

Reference yield:

: 184346-45-0
(S)-5,5-Diphenyl-4-isopropyl-1,3-oxazolidin-2-one

: 345904-96-3
N-[(1S,2S)-2-((S)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl)-2-methylsulfanyl-1-phenyl-ethyl]-2,4,6-trimethylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: BuLi / tetrahydrofuran / 0.17 h / 0 °C

1.2: 86 percent / tetrahydrofuran; dimethylsulfoxide / 4 h / 20 °C

2.1: BuLi / tetrahydrofuran / 0.08 h / -78 °C

2.2: tetrahydrofuran / 0.33 h / -100 - -78 °C

With n-butyllithium; In tetrahydrofuran;
DOI:10.1021/jo0155254

Reference yield:

: 345904-96-3
N-[(1S,2S)-2-((S)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl)-2-methylsulfanyl-1-phenyl-ethyl]-2,4,6-trimethylbenzenesulfonamide

: N-[(S)-2-Hydroxy-2-((S)-4-isopropyl-2-oxo-5,5-diphenyl-oxazolidin-3-yl)-1-phenyl-ethyl]-2,4,6-trimethyl-benzenesulfonamide

Guidance literature:: With mercury(II) trifluoroacetate; In tetrahydrofuran; water; acetonitrile; at 20 ℃; for 0.0833333h;
DOI:10.1021/jo0155254