Technology Process of 2,3,5,6-tetramethylphenylphenylphosphine
There total 1 articles about 2,3,5,6-tetramethylphenylphenylphosphine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2,3,5,6-tetramethylphenylmagnesium bromide; Dichlorophenylphosphine;
In
tetrahydrofuran;
at -80 - 20 ℃;
for 4h;
Inert atmosphere;
Schlenk technique;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 2h;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/ja501007t
- Guidance literature:
-
2,3,5,6-tetramethylphenylphenylphosphine; allyl bromide;
With
tetrakis(actonitrile)copper(I) hexafluorophosphate; (R,Rp)-1-(2-(diphenylphosphano)ferrocenyl)-1-(2-diphenylphosphanophenyl)-N,N-dimethylmethanamine; N,N,N′,N′-tetramethyl-N″-tert-butylguanidine; caesium carbonate;
In
1,2-dimethoxyethane;
at 0 ℃;
for 24h;
Inert atmosphere;
With
sulfur; acetic acid;
In
1,2-dimethoxyethane;
at 20 ℃;
for 0.5h;
enantioselective reaction;
Inert atmosphere;
DOI:10.1021/jacs.1c04112
- Guidance literature:
-
2,3,5,6-tetramethylphenylphenylphosphine; 1-Bromo-2-butyne;
With
tetrakis(actonitrile)copper(I) hexafluorophosphate; (R,Rp)-1-(2-(diphenylphosphano)ferrocenyl)-1-(2-diphenylphosphanophenyl)-N,N-dimethylmethanamine; caesium carbonate;
In
1,2-dimethoxyethane;
at 0 ℃;
for 24h;
Inert atmosphere;
With
sulfur; acetic acid;
In
1,2-dimethoxyethane;
at 20 ℃;
for 0.5h;
enantioselective reaction;
Inert atmosphere;
DOI:10.1021/jacs.1c04112
