3-(4-chlorophenyl)-2-(4-(8-aminooctylphenyl)thiazol-2-ylamino)propionic acid

Base Information

Chemical Name:3-(4-chlorophenyl)-2-(4-(8-aminooctylphenyl)thiazol-2-ylamino)propionic acid
CAS No.:1094765-51-1
Molecular Formula:C₂₆H₃₂ClN₃O₂S
Molecular Weight:486.078
Hs Code.:

Synonyms:3-(4-chlorophenyl)-2-(4-(8-aminooctylphenyl)thiazol-2-ylamino)propionic acid

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Chemical Property of 3-(4-chlorophenyl)-2-(4-(8-aminooctylphenyl)thiazol-2-ylamino)propionic acid

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Technology Process of 3-(4-chlorophenyl)-2-(4-(8-aminooctylphenyl)thiazol-2-ylamino)propionic acid

There total 10 articles about 3-(4-chlorophenyl)-2-(4-(8-aminooctylphenyl)thiazol-2-ylamino)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1094765-49-7
3-(4-chlorophenyl)-2-(4-(8-azidooctylphenyl)thiazol-2-ylamino)propionic acid

: 1094765-51-1
3-(4-chlorophenyl)-2-(4-(8-aminooctylphenyl)thiazol-2-ylamino)propionic acid

Guidance literature:: With hydrogen; palladium hydroxide on carbon; In methanol; chloroform; for 12h; under 760.051 Torr;

Reference yield:

: 1027102-02-8
2-[[[(ethoxycarbonyl)amino]thioxomethyl]amino]-3-(4-chlorophenyl)-propionic acid methyl ester

: 1094765-51-1
3-(4-chlorophenyl)-2-(4-(8-aminooctylphenyl)thiazol-2-ylamino)propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: water; sodium hydroxide / methanol / 0.5 h / Reflux

1.2: pH 3

2.1: N,N-dimethyl-formamide / 2 h / Inert atmosphere

3.1: hydrogen / palladium hydroxide on carbon / methanol; chloroform / 12 h / 760.05 Torr

With water; hydrogen; sodium hydroxide; palladium hydroxide on carbon; In methanol; chloroform; N,N-dimethyl-formamide;

Reference yield:

: 224775-70-6
8-(4-Acetylphenyl)octan-1-ol

: 1094765-51-1
3-(4-chlorophenyl)-2-(4-(8-aminooctylphenyl)thiazol-2-ylamino)propionic acid

Guidance literature:: Multi-step reaction with 5 steps

1: triethylamine / dichloromethane / 1 h / Inert atmosphere

2: sodium azide / N,N-dimethyl-formamide / 12 h / 80 °C

3: copper(ll) bromide / chloroform; ethyl acetate / Reflux

4: N,N-dimethyl-formamide / 2 h / Inert atmosphere

5: hydrogen / palladium hydroxide on carbon / methanol; chloroform / 12 h / 760.05 Torr

With sodium azide; hydrogen; triethylamine; copper(ll) bromide; palladium hydroxide on carbon; In methanol; dichloromethane; chloroform; ethyl acetate; N,N-dimethyl-formamide;