C₂₈H₃₂O₃P⁽¹⁺⁾*I^(1-)

Base Information

• Chemical Name: C₂₈H₃₂O₃P⁽¹⁺⁾*I^(1-)
• CAS No.: 1266178-64-6
• Molecular Formula: C₂₈H₃₂O₃P*I
• Molecular Weight: 574.439
• Mol file: 1266178-64-6.mol

Synonyms:C₂₈H₃₂O₃P⁽¹⁺⁾*I^(1-)

Chemical Property of C₂₈H₃₂O₃P⁽¹⁺⁾*I^(1-)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₃₂O₃P⁽¹⁺⁾*I^(1-)

There total 5 articles about C₂₈H₃₂O₃P⁽¹⁺⁾*I^(1-) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C10H17IO3 (1266178-63-5) + triphenylphosphine (603-35-0) → C28H32O3P(1+)*I(1-) (1266178-64-6)

Guidance literature:

In acetonitrile; at 150 ℃; for 2.5h; Microwave irradiation; Sealed tube; Inert atmosphere;

DOI:10.1002/anie.201005850

Reference yield:

2-((2S,4S)-2-(tert-butyl)-5-oxo-1,3-dioxolan-4-yl)acetic acid (56209-56-4) → C28H32O3P(1+)*I(1-) (1266178-64-6)

Guidance literature:

Multi-step reaction with 4 steps

1: lithium hexamethyldisilazane / tetrahydrofuran / -78 - 20 °C / Inert atmosphere

2: dimethylsulfide borane complex / tetrahydrofuran / -20 - 20 °C / Inert atmosphere

3: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h / Inert atmosphere

4: acetonitrile / 2.5 h / 150 °C / Microwave irradiation; Sealed tube; Inert atmosphere

With 1H-imidazole; dimethylsulfide borane complex; iodine; triphenylphosphine; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; acetonitrile;

DOI:10.1002/anie.201005850

Reference yield:

pivalaldehyde (630-19-3) → C28H32O3P(1+)*I(1-) (1266178-64-6)

Guidance literature:

Multi-step reaction with 5 steps

1: sulfuric acid / pentane / Inert atmosphere; Reflux

2: lithium hexamethyldisilazane / tetrahydrofuran / -78 - 20 °C / Inert atmosphere

3: dimethylsulfide borane complex / tetrahydrofuran / -20 - 20 °C / Inert atmosphere

4: 1H-imidazole; iodine; triphenylphosphine / dichloromethane / 3 h / Inert atmosphere

5: acetonitrile / 2.5 h / 150 °C / Microwave irradiation; Sealed tube; Inert atmosphere

With 1H-imidazole; dimethylsulfide borane complex; sulfuric acid; iodine; triphenylphosphine; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; acetonitrile; pentane;

DOI:10.1002/anie.201005850

upstream raw materials:

C₁₀H₁₇IO₃

triphenylphosphine

2-((2S,4S)-2-(tert-butyl)-5-oxo-1,3-dioxolan-4-yl)acetic acid

(2S,5S)-2-tert-butyl-5-(2-hydroxy-ethyl)-5-methyl-(1,3)dioxolan-4-one

Downstream raw materials:

C₁₉H₂₆O₃