Technology Process of C2HF3O2*C28H40N3O5PS2
There total 8 articles about C2HF3O2*C28H40N3O5PS2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / acetonitrile / 12 h / 22 °C
2: Resolution of racemate
3: dichloromethane / 2 h / 22 °C
With
O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine;
In
dichloromethane; acetonitrile;
DOI:10.1021/jm300599x
- Guidance literature:
-
Multi-step reaction with 7 steps
1: acetic acid / 2 h / 80 - 90 °C
2: hydrogen bromide; acetic acid / 2 h / 22 °C
3: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / acetonitrile / 12 h / 22 °C
4: dichloromethane / 2 h / 22 °C
5: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / acetonitrile / 12 h / 22 °C
6: Resolution of racemate
7: dichloromethane / 2 h / 22 °C
With
hydrogen bromide; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; acetic acid; N-ethyl-N,N-diisopropylamine;
In
dichloromethane; acetonitrile;
DOI:10.1021/jm300599x
- Guidance literature:
-
Multi-step reaction with 6 steps
1: hydrogen bromide; acetic acid / 2 h / 22 °C
2: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / acetonitrile / 12 h / 22 °C
3: dichloromethane / 2 h / 22 °C
4: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / acetonitrile / 12 h / 22 °C
5: Resolution of racemate
6: dichloromethane / 2 h / 22 °C
With
hydrogen bromide; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; acetic acid; N-ethyl-N,N-diisopropylamine;
In
dichloromethane; acetonitrile;
DOI:10.1021/jm300599x