phosphoric acid dibenzyl ester 8-methoxy-1-methyl-1H-benzo[de][1,6]naphthyridin-9-yl ester

Base Information

• Chemical Name: phosphoric acid dibenzyl ester 8-methoxy-1-methyl-1H-benzo[de][1,6]naphthyridin-9-yl ester
• CAS No.: 680615-39-8
• Molecular Formula: C₂₇H₂₅N₂O₅P
• Molecular Weight: 488.48
• Mol file: 680615-39-8.mol

Synonyms:phosphoric acid dibenzyl ester 8-methoxy-1-methyl-1H-benzo[de][1,6]naphthyridin-9-yl ester

Chemical Property of phosphoric acid dibenzyl ester 8-methoxy-1-methyl-1H-benzo[de][1,6]naphthyridin-9-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phosphoric acid dibenzyl ester 8-methoxy-1-methyl-1H-benzo[de][1,6]naphthyridin-9-yl ester

There total 2 articles about phosphoric acid dibenzyl ester 8-methoxy-1-methyl-1H-benzo[de][1,6]naphthyridin-9-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosphoric acid dibenzyl ester (1623-08-1) + 8-methoxy-1-methyl-1H-benzo[de][1,6]naphthyridin-9-ol hydrochloride → phosphoric acid dibenzyl ester 8-methoxy-1-methyl-1H-benzo[de][1,6]naphthyridin-9-yl ester (680615-39-8)

Guidance literature:

8-methoxy-1-methyl-1H-benzo[de][1,6]naphthyridin-9-ol hydrochloride; With N-ethyl-N,N-diisopropylamine; dmap; In tetrachloromethane; acetonitrile; at -10 ℃; for 0.0333333h;

phosphoric acid dibenzyl ester; In tetrachloromethane; acetonitrile; at -10 ℃; for 2h;

Reference yield:

Dibenzyl phosphite (17176-77-1) + 8-methoxy-1-methyl-1H-benzo[de][1,6]naphthyridin-9-ol hydrochloride → phosphoric acid dibenzyl ester 8-methoxy-1-methyl-1H-benzo[de][1,6]naphthyridin-9-yl ester (680615-39-8)

Guidance literature:

With dmap; N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; acetonitrile; at -10 ℃; for 2h;

DOI:10.1021/np0204592

upstream raw materials:

Dibenzyl phosphite

phosphoric acid dibenzyl ester