1-({3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)-3-(morpholin-4-ylmethyl)azetidin-3-ol trifluoroacetate salt

Base Information

Chemical Name:1-({3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)-3-(morpholin-4-ylmethyl)azetidin-3-ol trifluoroacetate salt
CAS No.:1035348-70-9
Molecular Formula:C₂HF₃O₂*C₂₁H₂₁F₃IN₃O₃
Molecular Weight:661.34
Hs Code.:

Synonyms:1-({3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)-3-(morpholin-4-ylmethyl)azetidin-3-ol trifluoroacetate salt

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-({3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)-3-(morpholin-4-ylmethyl)azetidin-3-ol trifluoroacetate salt

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 1-({3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)-3-(morpholin-4-ylmethyl)azetidin-3-ol trifluoroacetate salt

There total 2 articles about 1-({3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)-3-(morpholin-4-ylmethyl)azetidin-3-ol trifluoroacetate salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3-(morpholin-4-ylmethyl)azetidin-3-ol

: 934664-19-4
3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoyl fluoride

: 1035348-70-9
1-({3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)-3-(morpholin-4-ylmethyl)azetidin-3-ol trifluoroacetate salt

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

Reference yield:

: 3-(morpholin-4-ylmethyl)azetidin-3-ol

: 934664-19-4
3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoyl fluoride

: 76-05-1
trifluoroacetic acid

: 1035348-70-9
1-({3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonyl)-3-(morpholin-4-ylmethyl)azetidin-3-ol trifluoroacetate salt

Guidance literature:: 3-(morpholin-4-ylmethyl)azetidin-3-ol; 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoyl fluoride; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

trifluoroacetic acid;