(4S,5R)-5-(3-acetoxy-4-benzyloxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester

Base Information

Chemical Name:(4S,5R)-5-(3-acetoxy-4-benzyloxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester
CAS No.:821006-09-1
Molecular Formula:C₂₇H₂₅NO₇
Molecular Weight:475.498
Hs Code.:

Synonyms:(4S,5R)-5-(3-acetoxy-4-benzyloxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester

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Chemical Property of (4S,5R)-5-(3-acetoxy-4-benzyloxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester

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Technology Process of (4S,5R)-5-(3-acetoxy-4-benzyloxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester

There total 10 articles about (4S,5R)-5-(3-acetoxy-4-benzyloxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 556104-38-2
(4R,5R)-5-(3-acetoxy-4-benzyloxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester

: 821006-09-1
(4S,5R)-5-(3-acetoxy-4-benzyloxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester

Guidance literature:: With 1,8-diazabicyclo[5.4.0.]undec-7-ene; In dichloromethane; at 20 ℃; for 36h;
DOI:10.1021/ja710363p

Reference yield: 85.0%

: 67567-57-1
2-(p-methoxyphenyl)-5-methoxyoxazole

: 65299-01-6
acetic acid 2-benzyloxy-5-formylphenyl ester

: 821006-09-1
(4S,5R)-5-(3-acetoxy-4-benzyloxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester

: C₂₇H₂₅NO₇

: 556104-38-2
(4R,5R)-5-(3-acetoxy-4-benzyloxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester

Guidance literature:: With silver hexafluoroantimonate; 3 A molecular sieve; lithium perchlorate; (S)-salen-Al catalyst; In toluene; at 20 ℃; for 20h;
DOI:10.1021/ja710363p

Reference yield:

: 67567-57-1
2-(p-methoxyphenyl)-5-methoxyoxazole

: 65299-01-6
acetic acid 2-benzyloxy-5-formylphenyl ester

: 821006-09-1
(4S,5R)-5-(3-acetoxy-4-benzyloxyphenyl)-2-(4-methoxyphenyl)-4,5-dihydrooxazole-4-carboxylic acid methyl ester

: C₂₇H₂₅NO₇

Guidance literature:: With silver hexafluoroantimonate; lithium perchlorate; (R)-salen-Al catalyst; In toluene; at 20 ℃; for 20h;
DOI:10.1021/ja710363p