2-(Cyclopropylmethoxy)-3-iodopyridine

Base Information

• Chemical Name: 2-(Cyclopropylmethoxy)-3-iodopyridine
• CAS No.: 766557-62-4
• Molecular Formula: C₉H₁₀INO
• Molecular Weight: 275.089
• Hs Code.: 2933399090
• European Community (EC) Number: 676-888-4
• DSSTox Substance ID: DTXSID60590331
• Wikidata: Q82484048
• Mol file: 766557-62-4.mol

Synonyms:766557-62-4;2-Cyclopropylmethoxy-3-iodo-pyridine;2-(cyclopropylmethoxy)-3-iodopyridine;2-CYCLOPROPYLMETHOXY-3-IODOPYRIDINE;SCHEMBL760442;DTXSID60590331;ILSBVXOYWKUWLJ-UHFFFAOYSA-N;MFCD06659010;AKOS015840788;AB25870;AS-81333;2-(cyclopropylmethoxy)-3-iodanyl-pyridine;2-Cyclopropylmethoxy-3-iodo-pyridine, AldrichCPR;A838788;A1-38991;J-506345

Chemical Property of 2-(Cyclopropylmethoxy)-3-iodopyridine

Chemical Property:

• Vapor Pressure: 0.00165mmHg at 25°C
• Refractive Index: 1.623
• Boiling Point: 303.7ºC at 760 mmHg
• PKA: 2.01±0.22(Predicted)
• Flash Point: 137.5ºC
• PSA: 22.12000
• Density: 1.741g/cm3
• LogP: 2.47500
• Sensitive.: Light Sensitive
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 274.98071
• Heavy Atom Count: 12
• Complexity: 150

Purity/Quality:

97% ^*data from raw suppliers

2-Cyclopropylmethoxy-3-iodo-pyridine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1COC2=C(C=CC=N2)I

Technology Process of 2-(Cyclopropylmethoxy)-3-iodopyridine

There total 1 articles about 2-(Cyclopropylmethoxy)-3-iodopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

Cyclopropylmethanol (2516-33-8) + 2-fluoro-3-iodopyridine (113975-22-7) → 2-cyclopropylmethoxy-3-iodopyridine (766557-62-4)

Guidance literature:

Cyclopropylmethanol; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.5h;

2-fluoro-3-iodopyridine; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 1h;

upstream raw materials:

Cyclopropylmethanol

2-fluoro-3-iodopyridine