methyl 2-[2-(5-benzyl-4-phenyl-4H-[1,2,4]triazol-3-thio)-acetylamino]-3-(1H-indol-3-yl)-propionate

Base Information

• Chemical Name: methyl 2-[2-(5-benzyl-4-phenyl-4H-[1,2,4]triazol-3-thio)-acetylamino]-3-(1H-indol-3-yl)-propionate
• CAS No.: 1246371-81-2
• Molecular Formula: C₂₉H₂₇N₅O₃S
• Molecular Weight: 525.631
• Mol file: 1246371-81-2.mol

Synonyms:methyl 2-[2-(5-benzyl-4-phenyl-4H-[1,2,4]triazol-3-thio)-acetylamino]-3-(1H-indol-3-yl)-propionate

Chemical Property of methyl 2-[2-(5-benzyl-4-phenyl-4H-[1,2,4]triazol-3-thio)-acetylamino]-3-(1H-indol-3-yl)-propionate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-[2-(5-benzyl-4-phenyl-4H-[1,2,4]triazol-3-thio)-acetylamino]-3-(1H-indol-3-yl)-propionate

There total 1 articles about methyl 2-[2-(5-benzyl-4-phenyl-4H-[1,2,4]triazol-3-thio)-acetylamino]-3-(1H-indol-3-yl)-propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

(S)-tryptophan methyl ester hydrochloride (7524-52-9,26988-71-6,5619-09-0,14907-27-8,41222-70-2,67557-19-1,109492-62-8) + (5-benzyl-4-phenyl-4H-[1,2,4]triazol-3-thio)-acetic acid hydrazide (49656-92-0) → methyl 2-[2-(5-benzyl-4-phenyl-4H-[1,2,4]triazol-3-thio)-acetylamino]-3-(1H-indol-3-yl)-propionate (1246371-81-2)

Guidance literature:

(5-benzyl-4-phenyl-4H-[1,2,4]triazol-3-thio)-acetic acid hydrazide; With hydrogenchloride; acetic acid; sodium nitrite; In water; at -5 ℃; for 0.25h;

(S)-tryptophan methyl ester hydrochloride; With triethylamine; In ethyl acetate; at -5 - 25 ℃; for 48h;

DOI:10.3390/molecules15106759

upstream raw materials:

(S)-tryptophan methyl ester hydrochloride

(5-benzyl-4-phenyl-4H-[1,2,4]triazol-3-thio)-acetic acid hydrazide