1,1-dimethylethyl {2-[({5-[2-(3-furanyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)amino]-3-phenylpropyl}carbamate

Base Information

• Chemical Name: 1,1-dimethylethyl {2-[({5-[2-(3-furanyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)amino]-3-phenylpropyl}carbamate
• CAS No.: 943324-35-4
• Molecular Formula: C₃₆H₃₄N₄O₆S₂
• Molecular Weight: 682.821

Synonyms:1,1-dimethylethyl {2-[({5-[2-(3-furanyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)amino]-3-phenylpropyl}carbamate

Chemical Property of 1,1-dimethylethyl {2-[({5-[2-(3-furanyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)amino]-3-phenylpropyl}carbamate

Chemical Property:

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Technology Process of 1,1-dimethylethyl {2-[({5-[2-(3-furanyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)amino]-3-phenylpropyl}carbamate

There total 1 articles about 1,1-dimethylethyl {2-[({5-[2-(3-furanyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)amino]-3-phenylpropyl}carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

4-bromo-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (889939-26-8) + [5-({[2-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-1-(phenylmethyl)ethyl]amino}carbonyl)-2-thienyl]boronic acid (943324-31-0) → 1,1-dimethylethyl {2-[({5-[2-(3-furanyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)amino]-3-phenylpropyl}carbamate (943324-35-4)

Guidance literature:

With potassium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; water; at 70 ℃; for 12h;

Reference yield:

1,1-dimethylethyl {2-[({5-[2-(3-furanyl)-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-4-yl]-2-thienyl}carbonyl)amino]-3-phenylpropyl}carbamate (943324-35-4) → C30H30N4O4S

Guidance literature:

With methanol; sodium hydroxide; water; at 20 ℃; for 0.5h;

upstream raw materials:

4-bromo-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine

[5-({[2-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-1-(phenylmethyl)ethyl]amino}carbonyl)-2-thienyl]boronic acid

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