889939-26-8

Basic information

• Product Name: 4-BROMO-2-IODO-1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE
• Synonyms: 4-BROMO-2-IODO-1-BENZENSULFONYL-7-AZAINDOLE;4-BROMO-2-IODO-1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE;N-Tosyl-4-bromo-3-iodo-7-azaindole;1-(Phenylsulfonyl)-4-bromo-2-iodo-7-azaindole;1H-Pyrrolo[2,3-b]pyridine, 4-broMo-2-iodo-1-(phenylsulfonyl)-;1-(Phenylsulphonyl)-4-broMo-2-iodo-7-azaindole;1-(benzenesulfonyl)-4-bromo-2-iodo-1H-pyrrolo[2,3-b]pyridine;1-(benzenesulfonyl)-4-bromo-2-iodopyrrolo[2,3-b]pyridine
• CAS NO: 889939-26-8
• Molecular Formula: C₁₃H₈BrIN₂O₂S
• Molecular Weight: 463.09
• Mol File: 889939-26-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 572.196 °C at 760 mmHg
• Flash Point: 299.854 °C
• Appearance: /
• Density: 2.083g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.763
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 4-BROMO-2-IODO-1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-2-IODO-1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE(889939-26-8)
• EPA Substance Registry System: 4-BROMO-2-IODO-1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE(889939-26-8)

Safety Data

• Hazardous Substances Data: 889939-26-8(Hazardous Substances Data)

Usage

Uses

4-Bromo-2-iodo-1-(phenylsulfonyl)pyrrolo[2,3-b]pyridine was used to discover GSK1070916, a potent and selective inhibitor of Aurora B/C kinase.

InChI:InChI=1/C13H8BrIN2O2S/c14-11-6-7-16-13-10(11)8-12(15)17(13)20(18,19)9-4-2-1-3-5-9/h1-8H

Upstream product

• 1260879-70-6 4-bromo-2-iodo-1H-pyrrolo[2,3-b]pyridine 
• 98-09-9 benzenesulfonyl chloride 
• 348640-06-2 4-bromo-7-azaindole 
• 889939-25-7 1-(benzenesulfonyl)-4-bromo-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 942921-71-3 4-[4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]-benzaldehyde 
• 942920-20-9 tert-butyl 4-(4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)-5,6-dihydropyridine-1(2H)-carboxylate 
• 942921-06-4 4-(4-(4-bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-yl)phenyl)morpholine 
• 1260879-70-6 4-bromo-2-iodo-1H-pyrrolo[2,3-b]pyridine 

Relevant articles and documents

COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES

The invention relates to compounds of formula (II) for using in imaging and particularly for the diagnosis of neurodegenerative diseases

TETRACYCLIC CDK9 KINASE INHIBITORS

Disclosed are compounds of Formula (Ia), and pharmaceutically acceptable salts thereof, wherein X, Y, R1, R2, R3A, R3B, and R4 are as described herein. The compounds may be used as agents in the treatment of diseases, including cancer. Also disclosed are pharmaceutical compositions comprising one or more compounds of Formula (Ia).