methyl 2-[[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]-sulfonyl]butanoate

Base Information

Chemical Name:methyl 2-[[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]-sulfonyl]butanoate
CAS No.:287952-42-5
Molecular Formula:C₁₇H₂₂F₃NO₅S
Molecular Weight:409.427
Hs Code.:

Synonyms:methyl 2-[[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]-sulfonyl]butanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 2-[[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]-sulfonyl]butanoate

Chemical Property:

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Technology Process of methyl 2-[[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]-sulfonyl]butanoate

There total 4 articles about methyl 2-[[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]-sulfonyl]butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.0%

: bis-(2-bromoethyl)amine ethyl carbamate

: 287952-11-8
methyl [[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]sulfonyl]acetate

: 287952-42-5
methyl 2-[[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]-sulfonyl]butanoate

: 1520-70-3
Ethanesulfonamide

Guidance literature:: With potassium carbonate; In N-methyl-acetamide; ethyl acetate;

Reference yield:

: 287952-10-7
1-(methylsulfonyl)-4-[4-(trifluoromethyl)phenoxy]piperidine

: 287952-42-5
methyl 2-[[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]-sulfonyl]butanoate

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium chloride; lithium hexamethyldisilazane / tetrahydrofuran

2: potassium carbonate / N-methyl-acetamide; ethyl acetate

With ammonium chloride; potassium carbonate; lithium hexamethyldisilazane; In tetrahydrofuran; N-methyl-acetamide; ethyl acetate;

Reference yield:

: 28033-37-6
4-[4-(trifluoromethyl)-phenoxy]piperidine

: 287952-42-5
methyl 2-[[4-[4-(trifluoromethyl)phenoxy]-1-piperidinyl]-sulfonyl]butanoate

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / diethyl ether; dichloromethane; ethyl acetate

2: ammonium chloride; lithium hexamethyldisilazane / tetrahydrofuran

3: potassium carbonate / N-methyl-acetamide; ethyl acetate

With ammonium chloride; potassium carbonate; triethylamine; lithium hexamethyldisilazane; In tetrahydrofuran; N-methyl-acetamide; diethyl ether; dichloromethane; ethyl acetate;