triethyl 5,5',5-(benzene-1,3,5-triyl)tris(3-(2,4-dichlorophenyl)isoxazole-4-carboxylate)

Base Information

• Chemical Name: triethyl 5,5',5-(benzene-1,3,5-triyl)tris(3-(2,4-dichlorophenyl)isoxazole-4-carboxylate)
• CAS No.: 1610688-90-8
• Molecular Formula: C₄₂H₂₇Cl₆N₃O₉
• Molecular Weight: 930.409
• Mol file: 1610688-90-8.mol

Synonyms:triethyl 5,5',5-(benzene-1,3,5-triyl)tris(3-(2,4-dichlorophenyl)isoxazole-4-carboxylate)

Chemical Property of triethyl 5,5',5-(benzene-1,3,5-triyl)tris(3-(2,4-dichlorophenyl)isoxazole-4-carboxylate)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of triethyl 5,5',5-(benzene-1,3,5-triyl)tris(3-(2,4-dichlorophenyl)isoxazole-4-carboxylate)

There total 2 articles about triethyl 5,5',5-(benzene-1,3,5-triyl)tris(3-(2,4-dichlorophenyl)isoxazole-4-carboxylate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

(E)-ethyl 3-(2,4-dichlorophenyl)-5-(2-(dimethylamino)vinyl)isoxazole-4-carboxylate (1610688-75-9) → diethyl 5,5'-(4-(dimethylamino)buta-1,3-diene-1,3-diyl)bis(3-(2,4-dichlorophenyl)isoxazole-4-carboxylate) (1610688-82-8) + triethyl 5,5',5-(benzene-1,3,5-triyl)tris(3-(2,4-dichlorophenyl)isoxazole-4-carboxylate) (1610688-90-8)

Guidance literature:

With acetyl chloride; In 1,4-dioxane; at 20 ℃;

DOI:10.1016/j.tet.2014.04.015

Reference yield:

3-(2,4-dichloro-phenyl)-5-methyl-isoxazole-4-carboxylic acid ethyl ester (100726-70-3) → diethyl 5,5'-(4-(dimethylamino)buta-1,3-diene-1,3-diyl)bis(3-(2,4-dichlorophenyl)isoxazole-4-carboxylate) (1610688-82-8) + triethyl 5,5',5-(benzene-1,3,5-triyl)tris(3-(2,4-dichlorophenyl)isoxazole-4-carboxylate) (1610688-90-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1-methyl-1H-imidazole / 6 h / 80 °C

2: acetyl chloride / 1,4-dioxane / 20 °C

With 1-methyl-1H-imidazole; acetyl chloride; In 1,4-dioxane;

DOI:10.1016/j.tet.2014.04.015

upstream raw materials:

(E)-ethyl 3-(2,4-dichlorophenyl)-5-(2-(dimethylamino)vinyl)isoxazole-4-carboxylate

3-(2,4-dichloro-phenyl)-5-methyl-isoxazole-4-carboxylic acid ethyl ester