Technology Process of (3R)-6-(tert-butyldiphenylsiloxy)-3-methylhexanoic acid
There total 6 articles about (3R)-6-(tert-butyldiphenylsiloxy)-3-methylhexanoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium chlorite; sodium dihydrogenphosphate;
In
tert-butyl alcohol;
for 6h;
Yield given;
Ambient temperature;
DOI:10.1021/ja9533609
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) O3, 2.) BH3*SMe2 / 1.) CH2Cl2, -78 deg C, 2 h, 2.) CH2Cl2, 0 deg C, 3 h
2: 100 percent / DMAP, Et3N / CH2Cl2 / Ambient temperature
3: 100 percent / aq. K2CO3 / methanol / 4 h / Heating
4: 17.5 g / pyridinium dichromate, 4A molecular sieves / CH2Cl2 / 1 h / Ambient temperature
5: NaClO2, NaH2PO4*H2O / 2-methyl-propan-2-ol; various solvent(s) / 6 h / Ambient temperature
With
dmap; sodium chlorite; sodium dihydrogenphosphate; dipyridinium dichromate; dimethylsulfide borane complex; 4 A molecular sieve; potassium carbonate; ozone; triethylamine;
In
methanol; dichloromethane; tert-butyl alcohol;
DOI:10.1021/ja9533609
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 100 percent / pyridine, DMAP / CH2Cl2 / 0.75 h / 0 °C
2: 1.) O3, 2.) BH3*SMe2 / 1.) CH2Cl2, -78 deg C, 2 h, 2.) CH2Cl2, 0 deg C, 3 h
3: 100 percent / DMAP, Et3N / CH2Cl2 / Ambient temperature
4: 100 percent / aq. K2CO3 / methanol / 4 h / Heating
5: 17.5 g / pyridinium dichromate, 4A molecular sieves / CH2Cl2 / 1 h / Ambient temperature
6: NaClO2, NaH2PO4*H2O / 2-methyl-propan-2-ol; various solvent(s) / 6 h / Ambient temperature
With
pyridine; dmap; sodium chlorite; sodium dihydrogenphosphate; dipyridinium dichromate; dimethylsulfide borane complex; 4 A molecular sieve; potassium carbonate; ozone; triethylamine;
In
methanol; dichloromethane; tert-butyl alcohol;
DOI:10.1021/ja9533609
