(2S,3S)-1-<<(3-methylbutyl)carbonyl>amino>-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

Base Information

Chemical Name:(2S,3S)-1-<<(3-methylbutyl)carbonyl>amino>-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane
CAS No.:108868-58-2
Molecular Formula:C₂₁H₄₀N₂O₄
Molecular Weight:384.56
Hs Code.:

Synonyms:(2S,3S)-1-<<(3-methylbutyl)carbonyl>amino>-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

Suppliers and Price of (2S,3S)-1-<<(3-methylbutyl)carbonyl>amino>-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S)-1-<<(3-methylbutyl)carbonyl>amino>-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S)-1-<<(3-methylbutyl)carbonyl>amino>-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

There total 3 articles about (2S,3S)-1-<<(3-methylbutyl)carbonyl>amino>-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 38136-29-7
4-methylvaleroyl chloride

: 108868-91-3
(2S,3S)-1-amino-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane acetic acid salt

: 108868-58-2
(2S,3S)-1-<<(3-methylbutyl)carbonyl>amino>-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1021/jm00390a018

Reference yield:

: 107202-61-9
(2R,3S)-3-(t-butoxycarbonylamino)-4-cyclohexyl-1,2-epoxybutane

: 108868-58-2
(2S,3S)-1-<<(3-methylbutyl)carbonyl>amino>-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

Guidance literature:: Multi-step reaction with 3 steps

1: 57 percent / sodium azide, ammonium chloride / methanol / 16 h / Heating

2: 87 percent / H₂ / 10percent Pd/C / 9 h

3: 96 percent / Et₃N / CH₂Cl₂ / 1 h / 0 °C

With sodium azide; ammonium chloride; hydrogen; triethylamine; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/jm00390a018

Reference yield:

: 108868-89-9
(2S,3S)-1-azido-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

: 108868-58-2
(2S,3S)-1-<<(3-methylbutyl)carbonyl>amino>-2-hydroxy-3-<(tert-butyloxycarbonyl)amino>-4-cyclohexylbutane

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / H₂ / 10percent Pd/C / 9 h

2: 96 percent / Et₃N / CH₂Cl₂ / 1 h / 0 °C

With hydrogen; triethylamine; palladium on activated charcoal; In dichloromethane;
DOI:10.1021/jm00390a018