4-Chloro-1-<2-deoxy-5-O-(4-methoxytrityl)-β-D-erythropentofuranosyl>-1H-imidazo<4,5-c>pyridine

Base Information

Chemical Name:4-Chloro-1-<2-deoxy-5-O-(4-methoxytrityl)-β-D-erythropentofuranosyl>-1H-imidazo<4,5-c>pyridine
CAS No.:130948-30-0
Molecular Formula:C₃₁H₂₈ClN₃O₄
Molecular Weight:542.034
Hs Code.:

Synonyms:4-Chloro-1-<2-deoxy-5-O-(4-methoxytrityl)-β-D-erythropentofuranosyl>-1H-imidazo<4,5-c>pyridine

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Chemical Property of 4-Chloro-1-<2-deoxy-5-O-(4-methoxytrityl)-β-D-erythropentofuranosyl>-1H-imidazo<4,5-c>pyridine

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Technology Process of 4-Chloro-1-<2-deoxy-5-O-(4-methoxytrityl)-β-D-erythropentofuranosyl>-1H-imidazo<4,5-c>pyridine

There total 4 articles about 4-Chloro-1-<2-deoxy-5-O-(4-methoxytrityl)-β-D-erythropentofuranosyl>-1H-imidazo<4,5-c>pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 78582-15-7
4-chloro-1-(2'-deoxy-β-D-erythro-pentofuranosyl)-1H-imidazo<4,5-c>pyridine

: 14470-28-1
mono-4-methoxytrityl chloride

: 130948-30-0
4-Chloro-1-<2-deoxy-5-O-(4-methoxytrityl)-β-D-erythropentofuranosyl>-1H-imidazo<4,5-c>pyridine

Guidance literature:: With pyridine; silver nitrate; In tetrahydrofuran; for 3.5h; Ambient temperature;

Reference yield:

: 78582-13-5
4-Chloro-1-<2-deoxy-3,5-bis-O-(4-methylbenzoyl)-β-D-erythropentofuranosyl>-1H-imidazo<4,5-c>pyridine

: 130948-30-0
4-Chloro-1-<2-deoxy-5-O-(4-methoxytrityl)-β-D-erythropentofuranosyl>-1H-imidazo<4,5-c>pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / methanolic NH₃ / 16 h / Ambient temperature

2: 82 percent / AgNO₃, pyridine / tetrahydrofuran / 3.5 h / Ambient temperature

With pyridine; ammonia; silver nitrate; In tetrahydrofuran;

Reference yield:

: 2770-01-6
4-chloro-1H-imidazo[4,5-c]pyridine

: 130948-30-0
4-Chloro-1-<2-deoxy-5-O-(4-methoxytrityl)-β-D-erythropentofuranosyl>-1H-imidazo<4,5-c>pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 61 percent / KOH, tris-<2-(2-methoxyethoxy)ethyl>amine / acetonitrile / 1 h / Ambient temperature

2: 92 percent / methanolic NH₃ / 16 h / Ambient temperature

3: 82 percent / AgNO₃, pyridine / tetrahydrofuran / 3.5 h / Ambient temperature

With pyridine; potassium hydroxide; Tris(3,6-dioxaheptyl)amine; ammonia; silver nitrate; In tetrahydrofuran; acetonitrile;