C₁₆H₁₀ClNO₃

Base Information

• Chemical Name: C₁₆H₁₀ClNO₃
• CAS No.: 861236-56-8
• Molecular Formula: C₁₆H₁₀ClNO₃
• Molecular Weight: 299.713
• Mol file: 861236-56-8.mol

Synonyms:C₁₆H₁₀ClNO₃

Chemical Property of C₁₆H₁₀ClNO₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₆H₁₀ClNO₃

There total 1 articles about C₁₆H₁₀ClNO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

inden-1-one (83-33-0) + 2-chloro-5-nitrobenzaldehyde (6361-21-3) → C16H10ClNO3 (861236-56-8)

Guidance literature:

With potassium hydroxide; In ethanol; for 3h; Reflux;

DOI:10.1080/00397911.2013.804573

Reference yield: 72.0%

C16H10ClNO3 (861236-56-8) → C16H12ClNO3 (1485582-68-0)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; for 18h; chemoselective reaction; Reflux;

DOI:10.1080/00397911.2013.804573

Reference yield: 71.0%

C16H10ClNO3 (861236-56-8) + malononitrile (109-77-3) → 2-((R)-(2-chloro-5-nitrophenyl)((S)-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)malononitrile + 2-((S)-(2-chloro-5-nitrophenyl)((S)-1-oxo-2,3-dihydro-1H-inden-2-yl)methyl)malononitrile

Guidance literature:

With potassium tert-butylate; N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; at 20 ℃; for 6h;

DOI:10.1080/00397911.2017.1312450

upstream raw materials:

inden-1-one

2-chloro-5-nitrobenzaldehyde

Downstream raw materials:

C₁₆H₁₂ClNO₃