(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl benzoate

Base Information

Chemical Name:(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl benzoate
CAS No.:123632-51-9
Molecular Formula:C₁₃H₁₆O₇
Molecular Weight:284.266
Hs Code.:

Synonyms:(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl benzoate

Suppliers and Price of (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl benzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl benzoate

There total 9 articles about (2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 170428-69-0
C₁₂H₁₇NO₇

: 65-85-0,8013-63-6
benzoic acid

: 123632-51-9
(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl benzoate

: 21056-52-0
Benzoic acid (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl ester

Guidance literature:: In toluene; at 70 ℃; for 16h; optical yield given as %de; diastereoselective reaction;
DOI:10.1016/j.tetlet.2011.08.104

Reference yield:

: Benzoic acid (3R,4S,5R,6R)-3,4,5-tris-(2,2,2-trifluoro-acetoxy)-6-(2,2,2-trifluoro-acetoxymethyl)-tetrahydro-pyran-2-yl ester

: 123632-51-9
(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl benzoate

: 21056-52-0
Benzoic acid (2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yl ester

Guidance literature:: With sodium hydrogencarbonate; In methanol; Yield given. Yields of byproduct given;
DOI:10.1021/jo00259a006

Reference yield:

: 81342-44-1
(2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(2-(trimethylsilyl)ethoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate

: 123632-51-9
(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl benzoate

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / CH₃ONa / methanol / 3 h

2: CF₃COONa / 0.25 h / Heating

3: BF₃*Et₂O / toluene / 3 h / 55 °C

4: NaHCO₃ / methanol

With boron trifluoride diethyl etherate; sodium methylate; sodium 2,2,2-trifluoroacetate; sodium hydrogencarbonate; In methanol; toluene;
DOI:10.1021/jo00259a006