3-cyclopentyl-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionic acid

Base Information

Chemical Name:3-cyclopentyl-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionic acid
CAS No.:866774-36-9
Molecular Formula:C₁₉H₂₈N₂O₄S
Molecular Weight:380.508
Hs Code.:

Synonyms:3-cyclopentyl-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionic acid

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Chemical Property of 3-cyclopentyl-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionic acid

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Technology Process of 3-cyclopentyl-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionic acid

There total 1 articles about 3-cyclopentyl-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 866774-35-8
3-cyclopentyl-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionic acid ethyl ester

: 866774-36-9
3-cyclopentyl-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionic acid

Guidance literature:: With water; sodium hydroxide; In methanol; at 60 ℃; for 8h;
DOI:10.1021/jm900839k

Reference yield: 65.0%

: 13797-77-8
5-methoxythiazolo[5,4-b]pyridin-2-amine

: 866774-36-9
3-cyclopentyl-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionic acid

: 866772-51-2
3-cyclopentyl-N-(5-methoxy-thiazolo[5,4-b]pyridin-2-yl)-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionamide

Guidance literature:: 3-cyclopentyl-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionic acid; With 1-hydroxybenzotriazol-hydrate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 ℃; for 5h;

5-methoxythiazolo[5,4-b]pyridin-2-amine; With N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; at 0 - 28 ℃; for 75.5h;
DOI:10.1021/jm900839k

Reference yield:

: 866774-36-9
3-cyclopentyl-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionic acid

: 866774-37-0
(R)-(-)-3-cyclopentyl-2-[4-(4-methyl-piperazine-1-sulfonyl)-phenyl]-propionic acid

Guidance literature:: 3-cyclopentyl-2-[4-(4-methyl-piperazine-1-sulfonyl)phenyl]propionic acid; With (R)-1-phenyl-ethyl-amine; In 1,4-dioxane; at 27 - 100 ℃; for 44h; Resolution of racemate;

With hydrogenchloride; In water; for 0.0833333h;

With sodium hydrogencarbonate; In water; for 0.0833333h;