5,5-dimethyl-3-<2-(1,3-dioxolan-2-yl)-ethyl>-2-cyclohexen-1-one

Base Information

• Chemical Name: 5,5-dimethyl-3-<2-(1,3-dioxolan-2-yl)-ethyl>-2-cyclohexen-1-one
• CAS No.: 144648-12-4
• Molecular Formula: C₁₃H₂₀O₃
• Molecular Weight: 224.3
• Mol file: 144648-12-4.mol

Synonyms:5,5-dimethyl-3-<2-(1,3-dioxolan-2-yl)-ethyl>-2-cyclohexen-1-one

Chemical Property of 5,5-dimethyl-3-<2-(1,3-dioxolan-2-yl)-ethyl>-2-cyclohexen-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,5-dimethyl-3-<2-(1,3-dioxolan-2-yl)-ethyl>-2-cyclohexen-1-one

There total 2 articles about 5,5-dimethyl-3-<2-(1,3-dioxolan-2-yl)-ethyl>-2-cyclohexen-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimedone (126-81-8) → 5,5-dimethyl-3-<2-(1,3-dioxolan-2-yl)-ethyl>-2-cyclohexen-1-one (144648-12-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / conc. H₂SO₄ / 6 h / Heating

2: 1.) Mg, I₂, 1,2-dibromoethane / 1.) THF, 23 deg C, 1 h, 2.) THF, 23 deg C, overnight

With sulfuric acid; iodine; magnesium; ethylene dibromide;

DOI:10.1080/00397919208021553

Reference yield:

2-bromo-2-(2-ethyl)dioxolane (18742-02-4) + 3-methoxy-5,5-dimethyl-cyclohex-2-enone (4683-45-8) → 5,5-dimethyl-3-<2-(1,3-dioxolan-2-yl)-ethyl>-2-cyclohexen-1-one (144648-12-4)

Guidance literature:

With iodine; magnesium; ethylene dibromide; Yield given. Multistep reaction; 1.) THF, 23 deg C, 1 h, 2.) THF, 23 deg C, overnight;

DOI:10.1080/00397919208021553

Reference yield: 69.0%

5,5-dimethyl-3-<2-(1,3-dioxolan-2-yl)-ethyl>-2-cyclohexen-1-one (144648-12-4) → 5,5-dimethyl-3-oxo-1-cyclohexene-1-propanaldehyde (144648-13-5)

Guidance literature:

With hydrogenchloride; In acetone; for 40h; Ambient temperature;

DOI:10.1080/00397919208021553

upstream raw materials:

2-bromo-2-(2-ethyl)dioxolane

3-methoxy-5,5-dimethyl-cyclohex-2-enone

dimedone

Downstream raw materials:

5,5-dimethyl-3-oxo-1-cyclohexene-1-propanaldehyde

5,5-dimethyl-3-oxo-1-cyclohexene-1-propanoic acid