3-[3-(3-Bromomethyl-phenyl)-ureido]-benzenesulfonyl fluoride

Base Information

• Chemical Name: 3-[3-(3-Bromomethyl-phenyl)-ureido]-benzenesulfonyl fluoride
• CAS No.: 80936-81-8
• Molecular Formula: C₁₄H₁₂BrFN₂O₃S
• Molecular Weight: 387.229
• Mol file: 80936-81-8.mol

Synonyms:3-[3-(3-Bromomethyl-phenyl)-ureido]-benzenesulfonyl fluoride

Chemical Property of 3-[3-(3-Bromomethyl-phenyl)-ureido]-benzenesulfonyl fluoride

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3-[3-(3-Bromomethyl-phenyl)-ureido]-benzenesulfonyl fluoride

There total 3 articles about 3-[3-(3-Bromomethyl-phenyl)-ureido]-benzenesulfonyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-[3-(3-Methoxymethyl-phenyl)-ureido]-benzenesulfonyl fluoride (80936-72-7) → 3-[3-(3-Bromomethyl-phenyl)-ureido]-benzenesulfonyl fluoride (80936-81-8)

Guidance literature:

With hydrogen bromide; In acetic acid; at 100 ℃; for 0.166667h;

DOI:10.1021/jm00347a022

Reference yield:

m-(fluorosulfonyl)phenyl isocyanate (402-36-8) → 3-[3-(3-Bromomethyl-phenyl)-ureido]-benzenesulfonyl fluoride (80936-81-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / dioxane / 1 h

2: HBr / acetic acid / 0.17 h / 100 °C

With hydrogen bromide; In 1,4-dioxane; acetic acid;

DOI:10.1021/jm00347a022

Reference yield:

3-(1-methoxymethyl)phenylamine (53473-83-9) → 3-[3-(3-Bromomethyl-phenyl)-ureido]-benzenesulfonyl fluoride (80936-81-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 83 percent / dioxane / 1 h

2: HBr / acetic acid / 0.17 h / 100 °C

With hydrogen bromide; In 1,4-dioxane; acetic acid;

DOI:10.1021/jm00347a022

upstream raw materials:

3-[3-(3-Methoxymethyl-phenyl)-ureido]-benzenesulfonyl fluoride

m-(fluorosulfonyl)phenyl isocyanate

3-(1-methoxymethyl)phenylamine