53473-83-9

Usage

Uses

Used in Chemical Synthesis:
3-(Methoxymethyl)aniline is used as a key intermediate in the production of various organic compounds, including dyes, pharmaceuticals, and agricultural chemicals. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis of a wide range of products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-(Methoxymethyl)aniline is used as a building block for the development of new drugs. Its reactivity and functional groups enable the creation of diverse pharmaceutical compounds with potential therapeutic applications.
Used in Dye Industry:
3-(Methoxymethyl)aniline is used as a precursor in the synthesis of various dyes. Its chemical properties allow for the production of dyes with specific color characteristics and stability, making it an essential component in the dye manufacturing process.
Used in Agricultural Chemicals:
3-(Methoxymethyl)aniline is utilized in the development of agricultural chemicals, such as pesticides and herbicides. Its chemical structure contributes to the effectiveness of these products in controlling pests and promoting crop growth.
Used in Polymer Chemistry and Materials Science:
3-(Methoxymethyl)aniline has potential applications in the field of polymer chemistry and materials science. Its unique structure can be incorporated into polymers to create new materials with specific properties, such as improved strength, flexibility, or chemical resistance.

InChI:InChI=1/C8H11NO/c1-10-6-7-3-2-4-8(9)5-7/h2-5H,6,9H2,1H3

Upstream product

• 1515-84-0 1-(methoxymethyl)-3-nitrobenzene 
• 619-23-8 3-Nitrobenzyl chloride 
• 3958-57-4 1-bromomethyl-3-nitrobenzene 
• 619-25-0 3-Nitrobenzyl alcohol 
• 1877-77-6 3-aminobenzenemethanol 
• 74-88-4 methyl iodide 
• 74-83-9 methyl bromide 

Downstream Products

• 80936-72-7 3-[3-(3-Methoxymethyl-phenyl)-ureido]-benzenesulfonyl fluoride 
• 80936-71-6 4-[3-(3-Methoxymethyl-phenyl)-ureido]-benzenesulfonyl fluoride 
• 80936-81-8 3-[3-(3-Bromomethyl-phenyl)-ureido]-benzenesulfonyl fluoride 
• 80936-80-7 4-[3-(3-Bromomethyl-phenyl)-ureido]-benzenesulfonyl fluoride 
• 1260095-57-5 N₁,N₇-bis(3-methoxymethylphenyl)-4-(3-(3-methoxymethylphenylamino)-3-oxopropyl)-4-nitroheptanediamide 
• 1260095-65-5 N-(3-bromomethylphenyl)-3,4-dihydroxybenzamide 
• 1260095-69-9 4-tert-butyl-1-(3-(3,4-dihydroxybenzamido)benzyl)pyridinium bromide 
• 1260095-61-1 N-(3-methoxymethylphenyl)-2,2-diphenylbenzo[d][1,3]dioxole-5-carboxamide 
• 1260095-55-3 9H-fluoren-9-ylmethyl 1,7-bis(3-methoxymethylphenylamino)-4-(3-(3-methoxymethylphenylamino)-3-oxopropyl)-1,7-dioxoheptan-4-ylcarbamate 
• 1374643-76-1 4-methyl-N-(3-methoxymethyl-phenyl)-3-[4-(2,2,2-trifluoro-acetyl)-piperazin-1-yl]benzenesulfonamide 

Relevant academic research and scientific papers

Formation of highly charged quasi-molecular ions of a polycationic [60]fullerene hexakis-adduct and their fragmentation behavior in the gas phase

A novel polycationic [60]fullerene hexakis-adduct has been synthesized and investigated by electrospray ionization and tandem mass spectrometry. The polycationic ligand system comprises 12 pre-formed positive charges, compensated in the neutral molecule b

Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer

Provided are a liquid crystal alignment film capable of being given anisotropy through photoalignment and stable to light, and a liquid crystal display device capable of keeping a high voltage holding ratio without degradation of display quality even when

Efficient synthetic access to cationic dendrons and their application for ZnO nanoparticles surface functionalization: New building blocks for dye-sensitized solar cells

A new concept for the efficient synthesis of cationic dendrons, 4-tert-butyl-1-(3-(3,4-dihydroxybenzamido)benzyl)pyridinium bromide (17), 1,1′-(5-(3,4-dihydroxybenzamido)-1,3-phenylene)bis(methylene) bis(4-tert-butylpyridinium) bromide (18), N1,N7-bis(3-(

N-Phenyl-N′-(2-chloroethyl)ureas (CEU) as potential antineoplastic agents. Part 2: Role of ω-hydroxyl group in the covalent binding to β-tubulin

Tubulin is the target of many anticancer drugs, including N-phenyl-N′-(2-chloroethyl)urea (CEU). Unlike most anti-β-tubulin agents, CEUs are protein monoalkylating agents binding through their N′-(2-chloroethyl)urea moiety to an amino acid nearby the colchicine-binding site on β-tubulin isoform-2. Following the previously synthesized and attractive N-(3-ω-hydroxyalkylphenyl)-N′-(2-chloroethyl)urea that exhibited growth inhibitory activity at the nanomolar level, we investigated the importance of lower alkyl and alkoxy groups to evaluate the effect of hydroxylated group and chain length on both cell growth inhibition and the mechanism of action of CEU. Here, we describe the preparation of two new series of CEU and show that the most potent CEU derivatives beside the ω-hydroxylated 1f were 2f and 3e, respectively. We have confirmed that the pentyl substituted CEUs 1f, 2f, and 3e are still covalently binding to β-tubulin and still arrest cell division in G2/M phase. Crown Copyright

Bisphosphonate inhibition of the exopolyphosphatase activity of the Trypanosoma brucei soluble vacuolar pyrophosphatase

Trypanosoma brucei, the causative agent of African trypanosomiasis, contains a soluble, vacuolar pyrophosphatase, TbVSP1, not present in humans, which is essential for the growth of bloodstream forms in their mammalian host. Here, we report the inhibition of a recombinant TbVSP1 expressed in Escherichia coli by a panel of 81 bisphosphonates. The IC50 values were found to vary from ～2 to 850 μM. We then used 3D QSAR (comparative molecular field and comparative molecular similarity index; CoMFA and CoMSIA) methods to analyze the enzyme inhibition results. The R2 values for the experimental versus the QSAR-predicted activities were 0.78 or 0.61 for CoMFA and 0.79 or 0.68 for CoMSIA, for two different alignments. The root-mean-square (rms) pIC50 error for the best CoMFA model was 0.41 for five test sets of five activity predictions, which translates to a factor of ～2.6 error in IC50 prediction. For CoMSIA, the rms pIC50 error and error factors were 0.35 and 2.2, respectively. In general, the most active compounds contained both a single aromatic ring and a hydrogen bond donor feature. Thirteen of the more potent compounds were then tested in vivo in a mouse model of T. brucei infection. The most active compound in vivo provided a 40% protection from death with no apparent side effects, suggesting that further development of such compounds may be of interest.

Substituted N, N-disubstituted diamino compounds useful for inhibiting cholesteryl ester transfer protein activity

The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis and other coronary artery diseases. Preferred tertiary-heteroalkylamine compounds are substituted N,N-disubstituted diamines. A preferred specific N,N-disubstituted diamine is the compound:

N-Alkyl-N-[3-(alkoxyalkyl)phenyl]-2-haloacetamide herbicides

This invention concerns certain N-alkyl-N-[3-(alkoxyalkyl)phenyl]-2-haloacetamides having herbicidal activity, their preparation, and the control of weeds therewith.