1-Propanone,2-amino-1-(1-ethyl-1H-indol-3-yl)-2-methyl-(9CI)

Base Information

Chemical Name:1-Propanone,2-amino-1-(1-ethyl-1H-indol-3-yl)-2-methyl-(9CI)
CAS No.:761338-34-5
Molecular Formula:C₁₄H₁₈N₂O
Molecular Weight:230.31
Hs Code.:
Mol file:761338-34-5.mol

Synonyms:1-Propanone,2-amino-1-(1-ethyl-1H-indol-3-yl)-2-methyl-(9CI)

Suppliers and Price of 1-Propanone,2-amino-1-(1-ethyl-1H-indol-3-yl)-2-methyl-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 1-Propanone,2-amino-1-(1-ethyl-1H-indol-3-yl)-2-methyl-(9CI)

Chemical Property:

PSA：48.02000
LogP:3.28150

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-Propanone,2-amino-1-(1-ethyl-1H-indol-3-yl)-2-methyl-(9CI)

There total 5 articles about 1-Propanone,2-amino-1-(1-ethyl-1H-indol-3-yl)-2-methyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 117954-43-5
2-Azido-1-(1-ethyl-1H-indol-3-yl)-2-methyl-propan-1-one

: 761338-34-5
2-Amino-1-(1-ethyl-1H-indol-3-yl)-2-methyl-propan-1-one

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 8h; under 760 Torr; Yield given;

Reference yield:

: 120-72-9
indole

: 761338-34-5
2-Amino-1-(1-ethyl-1H-indol-3-yl)-2-methyl-propan-1-one

Guidance literature:: Multi-step reaction with 5 steps

1: 1. phenylmagnesium bromide / 1. benzene, 10 min.; 2. benzene, reflux, 1 h

2: 1. 54.3percent sodium hydride in mineral oil / 1. DMSO, 40 degC, until hydrogen evolution ceased; 2. below 30 degC, 15 min.

3: 76 percent / CuBr₂ / ethyl acetate; CHCl₃ / 18 h / Heating

4: 90 percent / sodium azide / dimethylsulfoxide / 2 h / 50 °C

5: hydrogen / 20percent Pd on carbon / methanol / 8 h / 760 Torr

With sodium azide; hydrogen; sodium hydride; phenylmagnesium bromide; copper(ll) bromide; palladium on activated charcoal; In methanol; chloroform; dimethyl sulfoxide; ethyl acetate;

Reference yield:

: 57642-07-6
1-(1H-indol-3-yl)-2-methylpropan-1-one

: 761338-34-5
2-Amino-1-(1-ethyl-1H-indol-3-yl)-2-methyl-propan-1-one

Guidance literature:: Multi-step reaction with 4 steps

1: 1. 54.3percent sodium hydride in mineral oil / 1. DMSO, 40 degC, until hydrogen evolution ceased; 2. below 30 degC, 15 min.

2: 76 percent / CuBr₂ / ethyl acetate; CHCl₃ / 18 h / Heating

3: 90 percent / sodium azide / dimethylsulfoxide / 2 h / 50 °C

4: hydrogen / 20percent Pd on carbon / methanol / 8 h / 760 Torr

With sodium azide; hydrogen; sodium hydride; copper(ll) bromide; palladium on activated charcoal; In methanol; chloroform; dimethyl sulfoxide; ethyl acetate;