Technology Process of (2R,3R,4S,5R)-5-Benzyloxy-4-methyl-heptane-1,2,3,4-tetraol
There total 10 articles about (2R,3R,4S,5R)-5-Benzyloxy-4-methyl-heptane-1,2,3,4-tetraol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 55 percent / NaH / tetrahydrofuran / 4 h / 21 °C
2: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 0 °C
3: 95 percent / acetic acid / H2O / 2 h / 115 °C
With
tetrabutyl ammonium fluoride; sodium hydride; acetic acid;
In
tetrahydrofuran; water;
DOI:10.1246/bcsj.62.2618
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 97 percent / imidazole / dimethylformamide / 2.66 h / 24 °C
2: pyridinium chlorochromate, molecular sieves 3 Angstroem / CH2Cl2 / 2 h / 22 °C
3: 85 percent / magnesium powder / tetrahydrofuran / 3 h / Ambient temperature
4: 1.) O3, 2.) dimethyl sulfide / 1.) methylene dichloride, -78 deg C, 2.) room temperature
5: 88 percent / magnesium powder / diethyl ether / 1.5 h / 0 °C
6: 55 percent / NaH / tetrahydrofuran / 4 h / 21 °C
7: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1 h / 0 °C
8: 95 percent / acetic acid / H2O / 2 h / 115 °C
With
1H-imidazole; dimethylsulfide; 3 A molecular sieve; tetrabutyl ammonium fluoride; sodium hydride; ozone; magnesium; acetic acid; pyridinium chlorochromate;
In
tetrahydrofuran; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1246/bcsj.62.2618
![(2R,3R)-3-Benzyloxy-2-((4R,5R)-5-hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-pentan-2-ol](/Databaselist/images/loading.webp)
