4,4,5,5-tetramethyl-2-(3-methylphenethyl)-1,3,2-dioxaborolane

Base Information

• Chemical Name: 4,4,5,5-tetramethyl-2-(3-methylphenethyl)-1,3,2-dioxaborolane
• CAS No.: 1431792-81-2
• Molecular Formula: C₁₅H₂₃BO₂
• Molecular Weight: 246.157
• Mol file: 1431792-81-2.mol

Synonyms:4,4,5,5-tetramethyl-2-(3-methylphenethyl)-1,3,2-dioxaborolane

Chemical Property of 4,4,5,5-tetramethyl-2-(3-methylphenethyl)-1,3,2-dioxaborolane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4,5,5-tetramethyl-2-(3-methylphenethyl)-1,3,2-dioxaborolane

There total 6 articles about 4,4,5,5-tetramethyl-2-(3-methylphenethyl)-1,3,2-dioxaborolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-methylstyrene (100-80-1) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 4,4,5,5-tetramethyl-2-(3-methylphenethyl)-1,3,2-dioxaborolane (1431792-81-2)

Guidance literature:

With calcium chloride; In chloroform-d1; at 110 ℃; for 12h; Glovebox;

Reference yield: 65.0%

bis(pinacol)diborane (73183-34-3) + 3-Methylacetophenone (585-74-0) → 4,4,5,5-tetramethyl-2-(3-methylphenethyl)-1,3,2-dioxaborolane (1431792-81-2)

Guidance literature:

With chloro(1,5-cyclooctadiene)rhodium(I) dimer; tributylphosphine; potassium formate; isopropyl alcohol; at 70 ℃; for 12h; regioselective reaction;

DOI:10.1021/acscatal.1c02685

Reference yield: 46.0%

3-methylstyrene (100-80-1) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 4,4,5,5-tetramethyl-2-(3-methylphenethyl)-1,3,2-dioxaborolane (1431792-81-2) + 2-(1-(3-methylphenyl)ethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:

With tris[3,5-bis(trifluoromethyl)phenyl]-borane; In neat (no solvent); at 50 ℃; for 24h; regioselective reaction; Glovebox; Inert atmosphere;

DOI:10.1002/chem.201603466

upstream raw materials:

3-methylstyrene

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

bis(pinacol)diborane

3-Methylacetophenone

Downstream raw materials:

potassium trifluoro(3-methylphenethyl)borate