Technology Process of (S)-N-[1-(2,4,6-triisopropylphenyl)ethyl]hydroxylamine
There total 7 articles about (S)-N-[1-(2,4,6-triisopropylphenyl)ethyl]hydroxylamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydroxylamine hydrochloride;
In
methanol;
at 60 ℃;
for 18h;
DOI:10.1021/jo061976i
- Guidance literature:
-
Multi-step reaction with 6 steps
1: hydrogen / palladium on carbon / ethanol / 64 h
2: 16.03 g / pyridine / CH2Cl2 / 13 h / 20 °C
3: 90 percent / KOH / ethane-1,2-diol / Heating
4: 91 percent / potassium carbonate / dimethylformamide / 5 h / 20 °C
5: 88 percent / m-chloroperbenzoic acid / CH2Cl2 / 19 h / 40 °C
6: 74 percent / hydroxylamine hydrochloride / methanol / 18 h / 60 °C
With
pyridine; potassium hydroxide; hydroxylamine hydrochloride; hydrogen; potassium carbonate; 3-chloro-benzenecarboperoxoic acid;
palladium on activated charcoal;
In
methanol; ethanol; dichloromethane; ethylene glycol; N,N-dimethyl-formamide;
DOI:10.1021/jo061976i
- Guidance literature:
-
Multi-step reaction with 7 steps
1: triphenylphosphine; Zn(N3)2(pyridine)2; diisopropyl azodicarboxylate / toluene / 48 h / 20 °C
2: hydrogen / palladium on carbon / ethanol / 64 h
3: 16.03 g / pyridine / CH2Cl2 / 13 h / 20 °C
4: 90 percent / KOH / ethane-1,2-diol / Heating
5: 91 percent / potassium carbonate / dimethylformamide / 5 h / 20 °C
6: 88 percent / m-chloroperbenzoic acid / CH2Cl2 / 19 h / 40 °C
7: 74 percent / hydroxylamine hydrochloride / methanol / 18 h / 60 °C
With
pyridine; potassium hydroxide; Zn(N3)2/bis-pyridine complex; di-isopropyl azodicarboxylate; hydroxylamine hydrochloride; hydrogen; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine;
palladium on activated charcoal;
In
methanol; ethanol; dichloromethane; ethylene glycol; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo061976i
