benzhydryl (S)-1-(2,4-dinitrophenylsulfonyl)-3,3-dimethylaziridine-2-carboxylate

Base Information

Chemical Name:benzhydryl (S)-1-(2,4-dinitrophenylsulfonyl)-3,3-dimethylaziridine-2-carboxylate
CAS No.:1275621-83-4
Molecular Formula:C₂₄H₂₁N₃O₈S
Molecular Weight:511.512
Hs Code.:

Synonyms:benzhydryl (S)-1-(2,4-dinitrophenylsulfonyl)-3,3-dimethylaziridine-2-carboxylate

Suppliers and Price of benzhydryl (S)-1-(2,4-dinitrophenylsulfonyl)-3,3-dimethylaziridine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of benzhydryl (S)-1-(2,4-dinitrophenylsulfonyl)-3,3-dimethylaziridine-2-carboxylate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of benzhydryl (S)-1-(2,4-dinitrophenylsulfonyl)-3,3-dimethylaziridine-2-carboxylate

There total 6 articles about benzhydryl (S)-1-(2,4-dinitrophenylsulfonyl)-3,3-dimethylaziridine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1275621-82-3
benzhydryl (S)-2-(2,4-dinitrophenylsulfonamido)-3-hydroxy-3-methylbutanoate

: 1275621-83-4
benzhydryl (S)-1-(2,4-dinitrophenylsulfonyl)-3,3-dimethylaziridine-2-carboxylate

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In toluene; at 20 ℃; for 19h;
DOI:10.1002/anie.201004646

Reference yield:

: 1275621-81-2
(S)-1-(benzhydryloxy)-3-hydroxy-3-methyl-1-oxobutan-2-aminium chloride

: 1275621-83-4
benzhydryl (S)-1-(2,4-dinitrophenylsulfonyl)-3,3-dimethylaziridine-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / tetrahydrofuran; water / 0 - 20 °C

2: di-isopropyl azodicarboxylate; triphenylphosphine / toluene / 19 h / 20 °C

With di-isopropyl azodicarboxylate; sodium carbonate; triphenylphosphine; In tetrahydrofuran; water; toluene; 2: Mitsunobu reaction;
DOI:10.1002/anie.201004646

Reference yield:

: 473545-40-3
tert-butyl N-[(1R)-2-hydroxy-1-(hydroxymethyl)-2-methylpropyl]carbamate

: 1275621-83-4
benzhydryl (S)-1-(2,4-dinitrophenylsulfonyl)-3,3-dimethylaziridine-2-carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: sodium chlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene / acetonitrile / 0 - 20 °C / pH 6.4 / aq. phosphate buffer

2: dichloromethane / 0 - 20 °C

3: hydrogenchloride / methanol / 1 h / -10 °C

4: sodium carbonate / tetrahydrofuran; water / 0 - 20 °C

5: di-isopropyl azodicarboxylate; triphenylphosphine / toluene / 19 h / 20 °C

With hydrogenchloride; sodium chlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; di-isopropyl azodicarboxylate; sodium carbonate; triphenylphosphine; In tetrahydrofuran; methanol; dichloromethane; water; toluene; acetonitrile; 5: Mitsunobu reaction;
DOI:10.1002/anie.201004646