(6-{4-[2-(2-trimethylsilanyl-ethoxymethyl)-2H-pyrazol-3-yl]-phenoxy}-imidazo[1,2-a]pyridin-2-yl)-methanol

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Chemical Name:(6-{4-[2-(2-trimethylsilanyl-ethoxymethyl)-2H-pyrazol-3-yl]-phenoxy}-imidazo[1,2-a]pyridin-2-yl)-methanol
CAS No.:1541188-74-2
Molecular Formula:C₂₃H₂₈N₄O₃Si
Molecular Weight:436.586
Hs Code.:

Synonyms:(6-{4-[2-(2-trimethylsilanyl-ethoxymethyl)-2H-pyrazol-3-yl]-phenoxy}-imidazo[1,2-a]pyridin-2-yl)-methanol

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Chemical Property of (6-{4-[2-(2-trimethylsilanyl-ethoxymethyl)-2H-pyrazol-3-yl]-phenoxy}-imidazo[1,2-a]pyridin-2-yl)-methanol

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Technology Process of (6-{4-[2-(2-trimethylsilanyl-ethoxymethyl)-2H-pyrazol-3-yl]-phenoxy}-imidazo[1,2-a]pyridin-2-yl)-methanol

There total 6 articles about (6-{4-[2-(2-trimethylsilanyl-ethoxymethyl)-2H-pyrazol-3-yl]-phenoxy}-imidazo[1,2-a]pyridin-2-yl)-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1541188-73-1
C₂₅H₃₀N₄O₄Si

: 1541188-74-2
(6-{4-[2-(2-trimethylsilanyl-ethoxymethyl)-2H-pyrazol-3-yl]-phenoxy}-imidazo[1,2-a]pyridin-2-yl)-methanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 25 ℃; for 3h;

Reference yield:

: 1541188-29-7
5-[4-[2-(2-trimethylsilylethoxymethyl)pyrazol-3-yl]phenoxy]pyridin-2-amine

: 1541188-74-2
(6-{4-[2-(2-trimethylsilanyl-ethoxymethyl)-2H-pyrazol-3-yl]-phenoxy}-imidazo[1,2-a]pyridin-2-yl)-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 4 h / 60 °C

2: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 25 °C

With lithium aluminium tetrahydride; In tetrahydrofuran;

Reference yield:

: C₂₀H₂₄N₄O₄Si

: 1541188-74-2
(6-{4-[2-(2-trimethylsilanyl-ethoxymethyl)-2H-pyrazol-3-yl]-phenoxy}-imidazo[1,2-a]pyridin-2-yl)-methanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: palladium 10% on activated carbon; hydrogen / methanol / 3 h

2.1: tetrahydrofuran / 4 h / 60 °C / Inert atmosphere

3.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 25 °C / Inert atmosphere

3.2: 0.25 h

With lithium aluminium tetrahydride; palladium 10% on activated carbon; hydrogen; In tetrahydrofuran; methanol;