5-chloro-2-([(2-([3-(furan-2-yl)phenyl]amino)-2-oxoethoxy)acetyl]amino)benzoic acid

Base Information

Chemical Name:5-chloro-2-([(2-([3-(furan-2-yl)phenyl]amino)-2-oxoethoxy)acetyl]amino)benzoic acid
CAS No.:1190221-46-5
Molecular Formula:C₂₁H₁₇ClN₂O₆
Molecular Weight:428.829
Hs Code.:

Synonyms:5-chloro-2-([(2-([3-(furan-2-yl)phenyl]amino)-2-oxoethoxy)acetyl]amino)benzoic acid

Suppliers and Price of 5-chloro-2-([(2-([3-(furan-2-yl)phenyl]amino)-2-oxoethoxy)acetyl]amino)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 4 raw suppliers

Chemical Property of 5-chloro-2-([(2-([3-(furan-2-yl)phenyl]amino)-2-oxoethoxy)acetyl]amino)benzoic acid

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

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Technology Process of 5-chloro-2-([(2-([3-(furan-2-yl)phenyl]amino)-2-oxoethoxy)acetyl]amino)benzoic acid

There total 3 articles about 5-chloro-2-([(2-([3-(furan-2-yl)phenyl]amino)-2-oxoethoxy)acetyl]amino)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1190222-72-0
methyl 5-chloro-2-{[(2-{[3-(furan-2-yl)phenyl]amino}-2-oxoethoxy)acetyl]amino}benzoate

: 1190221-46-5
5-chloro-2-([(2-([3-(furan-2-yl)phenyl]amino)-2-oxoethoxy)acetyl]amino)benzoic acid

Guidance literature:: With water; sodium hydroxide; In tetrahydrofuran; at 50 ℃; for 3h;
DOI:10.1016/j.bmcl.2017.11.016

Reference yield:

: 1103929-71-0
(2-{[4-chloro-2-(methoxycarbonyl)phenyl]amino}-2-oxoethoxy)acetic acid

: 1172481-22-9
3-(furan-2-yl)aniline hydrochloride

: 1190221-46-5
5-chloro-2-([(2-([3-(furan-2-yl)phenyl]amino)-2-oxoethoxy)acetyl]amino)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; triethylamine / N,N-dimethyl acetamide / 20 °C

2: sodium hydroxide; water / tetrahydrofuran / 3 h / 50 °C

With water; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; sodium hydroxide; In tetrahydrofuran; N,N-dimethyl acetamide;
DOI:10.1016/j.bmcl.2017.11.016