1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-D-erythro-pentafuranose

Base Information

Chemical Name:1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-D-erythro-pentafuranose
CAS No.:152963-78-5
Molecular Formula:C₂₃H₂₉FO₄Si
Molecular Weight:416.565
Hs Code.:

Synonyms:1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-D-erythro-pentafuranose

Suppliers and Price of 1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-D-erythro-pentafuranose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-D-erythro-pentafuranose

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-D-erythro-pentafuranose

There total 5 articles about 1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-D-erythro-pentafuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 108-24-7
acetic anhydride

: 5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-D-erythro-pentafuranose

: 152963-78-5
1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-D-erythro-pentafuranose

Guidance literature:: With dmap; In dichloromethane; Ambient temperature;
DOI:10.1246/bcsj.68.1509

Reference yield:

: 102717-31-7
(2S,4S)-5-(t-butyldiphenylsiloxy)-2-hydroxypentan-4-olide

: 152963-78-5
1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-D-erythro-pentafuranose

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / (dimethylamino)sulfurtrifluoride / CH₂Cl₂ / 2.5 h / Ambient temperature

2: 94 percent / DIBAL-H / tetrahydrofuran / 3 h / -78 °C

3: 100 percent / DMAP / CH₂Cl₂ / Ambient temperature

With dmap; dimethylaminosulphur trifluoride; diisobutylaluminium hydride; In tetrahydrofuran; dichloromethane;
DOI:10.1246/bcsj.68.1509

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 152963-78-5
1-O-acetyl-5-O-(t-butyldiphenylsilyl)-2,3-dideoxy-2-fluoro-D-erythro-pentafuranose

Guidance literature:: Multi-step reaction with 4 steps

1: 69 percent / imidazole / dimethylformamide / 2.4 h / Ambient temperature

2: 60 percent / (dimethylamino)sulfurtrifluoride / CH₂Cl₂ / 2.5 h / Ambient temperature

3: 94 percent / DIBAL-H / tetrahydrofuran / 3 h / -78 °C

4: 100 percent / DMAP / CH₂Cl₂ / Ambient temperature

With 1H-imidazole; dmap; dimethylaminosulphur trifluoride; diisobutylaluminium hydride; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1246/bcsj.68.1509