8,12,16-Tris-(toluene-4-sulfonyl)-1,4-dioxa-8,12,16-triaza-spiro[4.13]octadecane

Base Information

Chemical Name:8,12,16-Tris-(toluene-4-sulfonyl)-1,4-dioxa-8,12,16-triaza-spiro[4.13]octadecane
CAS No.:164987-81-9
Molecular Formula:C₃₄H₄₅N₃O₈S₃
Molecular Weight:719.945
Hs Code.:

Synonyms:8,12,16-Tris-(toluene-4-sulfonyl)-1,4-dioxa-8,12,16-triaza-spiro[4.13]octadecane

Suppliers and Price of 8,12,16-Tris-(toluene-4-sulfonyl)-1,4-dioxa-8,12,16-triaza-spiro[4.13]octadecane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 8,12,16-Tris-(toluene-4-sulfonyl)-1,4-dioxa-8,12,16-triaza-spiro[4.13]octadecane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 8,12,16-Tris-(toluene-4-sulfonyl)-1,4-dioxa-8,12,16-triaza-spiro[4.13]octadecane

There total 1 articles about 8,12,16-Tris-(toluene-4-sulfonyl)-1,4-dioxa-8,12,16-triaza-spiro[4.13]octadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35980-64-4
1,5,9-Tritosyl-1,5,9-triazanonane

: 164987-79-5
1,5-Dibromopentan-3-one ethylene ketal

: 164987-81-9
8,12,16-Tris-(toluene-4-sulfonyl)-1,4-dioxa-8,12,16-triaza-spiro[4.13]octadecane

Guidance literature:: With caesium carbonate; Yield given. Multistep reaction; 1.) DMF, 100 deg C, 3 h, 2.) DMF;
DOI:10.1021/ja00125a005

Reference yield: 96.0%

: 164987-81-9
8,12,16-Tris-(toluene-4-sulfonyl)-1,4-dioxa-8,12,16-triaza-spiro[4.13]octadecane

: 164987-87-5
1,5,9-tris(p-tolylsulfonyl)-1,5,9-triazacyclotetradec-12-one

Guidance literature:: With perchloric acid; In dichloromethane; for 2h; Ambient temperature;
DOI:10.1021/ja00125a005

Reference yield:

: 164987-81-9
8,12,16-Tris-(toluene-4-sulfonyl)-1,4-dioxa-8,12,16-triaza-spiro[4.13]octadecane

: S,S'-bis(12-(1,5,9-triazacyclododecyl))-1',4'-dithiobenzene

Guidance literature:: Multi-step reaction with 9 steps

1: 96 percent / 69percent aq. HClO₄ / CH₂Cl₂ / 2 h / Ambient temperature

2: 91 percent / NaBH₄ / ethanol / 15 h / Ambient temperature

3: 1.) NaH, imidazole / 1.) THF, reflux, 2 h, 2.) THF, reflux, 3 h

4: 79 percent / Li/NH₃ (liquid) / tetrahydrofuran / from -78 deg C to reflux

5: diisopropylethylamine / CH₂Cl₂ / 0.5 h / 0 - 20 °C

6: 81 percent / BBr₃ / CH₂Cl₂ / 0.25 h / 0 - 20 °C

7: diisopropylethylamine / CH₂Cl₂ / 0.25 h / 0 °C

8: 1.) NaH / 1.) dimethylimidazolone, 2.) dimethylimidazolone, 45 deg C, overnight

9: NH₃, CH₃OH

With 1H-imidazole; methanol; sodium tetrahydroborate; perchloric acid; ammonia; boron tribromide; lithium; sodium hydride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1021/ja00125a005