3-Furoic acid, tetrahydro-4-hydroxy-2-methyl- (5CI)

Base Information

• Chemical Name: 3-Furoic acid, tetrahydro-4-hydroxy-2-methyl- (5CI)
• CAS No.: 758726-13-5
• Molecular Formula: C₆H₁₀O₄
• Molecular Weight: 146.143
• Mol file: 758726-13-5.mol

Synonyms:3-Furoic acid, tetrahydro-4-hydroxy-2-methyl- (5CI)

Chemical Property of 3-Furoic acid, tetrahydro-4-hydroxy-2-methyl- (5CI)

Chemical Property:

• PSA: 66.76000
• LogP: -0.53320

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Furoic acid, tetrahydro-4-hydroxy-2-methyl- (5CI)

There total 2 articles about 3-Furoic acid, tetrahydro-4-hydroxy-2-methyl- (5CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxy-2-methyl-tetrahydro-furan-3-carboxylic acid ethyl ester → 4-hydroxy-2-methyl-tetrahydro-furan-3-carboxylic acid (758726-13-5)

Guidance literature:

With potassium hydroxide; optically inactive 4-hydroxy-2-methyl-tetrahydro-furan-3-carboxylic acid of mp: 109;

DOI:10.1002/hlca.19520350405

Reference yield:

ethyl 2-methyl-4-oxo-4,5-dihydrofuran-3-carboxylate (3511-34-0) → 4-hydroxy-2-methyl-tetrahydro-furan-3-carboxylic acid (758726-13-5)

Guidance literature:

Multi-step reaction with 2 steps

1: platinum; ethanol / Hydrogenation

2: methanol. KOH-solution

With potassium hydroxide; ethanol; platinum;

DOI:10.1002/hlca.19520350405

upstream raw materials:

ethyl 2-methyl-4-oxo-4,5-dihydrofuran-3-carboxylate