(S)-2-((tert-butoxycarbonyl)amino)-3-((1-(((2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-6-methoxytetrahydro-2H-pyran-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methoxy)propanoic acid

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Chemical Name:(S)-2-((tert-butoxycarbonyl)amino)-3-((1-(((2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-6-methoxytetrahydro-2H-pyran-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methoxy)propanoic acid
CAS No.:1316262-44-8
Molecular Formula:C₃₉H₄₈N₄O₁₀
Molecular Weight:732.831
Hs Code.:

(S)-2-((tert-butoxycarbonyl)amino)-3-((1-(((2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-6-methoxytetrahydro-2H-pyran-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methoxy)propanoic acid

Synonyms:(S)-2-((tert-butoxycarbonyl)amino)-3-((1-(((2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-6-methoxytetrahydro-2H-pyran-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methoxy)propanoic acid

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Chemical Property of (S)-2-((tert-butoxycarbonyl)amino)-3-((1-(((2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-6-methoxytetrahydro-2H-pyran-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methoxy)propanoic acid

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Technology Process of (S)-2-((tert-butoxycarbonyl)amino)-3-((1-(((2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-6-methoxytetrahydro-2H-pyran-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methoxy)propanoic acid

There total 2 articles about (S)-2-((tert-butoxycarbonyl)amino)-3-((1-(((2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-6-methoxytetrahydro-2H-pyran-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methoxy)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1236198-60-9
2-(tert-butoxycarbonylamino)-3-((1-(((2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-6-methoxytetrahydro-2H-pyran-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methoxy)propanoate benzyl ester

: 1316262-44-8
(S)-2-((tert-butoxycarbonyl)amino)-3-((1-(((2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-6-methoxytetrahydro-2H-pyran-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methoxy)propanoic acid

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; for 0.333333h;
DOI:10.1016/j.bmc.2011.05.049

Reference yield:

: 1190744-99-0
benzyl N-(tert-butoxycarbonyl)-O-(prop-2-yn-1-yl)-L-serinate

: 220129-77-1
1-methyl-6-azido-2,3,4-tri-O-benzyl-6-deoxy-α-D-mannopyranoside

: 1316262-44-8
(S)-2-((tert-butoxycarbonyl)amino)-3-((1-(((2R,3R,4S,5S,6S)-3,4,5-tris(benzyloxy)-6-methoxytetrahydro-2H-pyran-2-yl)methyl)-1H-1,2,3-triazol-4-yl)methoxy)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: copper(ll) sulfate pentahydrate; sodium L-ascorbate / dichloromethane; water / 8 h / 20 °C

2: palladium 10% on activated carbon; hydrogen / methanol / 0.33 h

With copper(ll) sulfate pentahydrate; palladium 10% on activated carbon; hydrogen; sodium L-ascorbate; In methanol; dichloromethane; water;
DOI:10.1016/j.bmc.2011.05.049