tert-butyldiphenylsilyl 4,6-di-O-benzyl-β-D-galactopyranosyl-(1->3)-2-azido-2-deoxy-β-D-galactopyranoside

Base Information

Chemical Name:tert-butyldiphenylsilyl 4,6-di-O-benzyl-β-D-galactopyranosyl-(1->3)-2-azido-2-deoxy-β-D-galactopyranoside
CAS No.:187157-57-9
Molecular Formula:C₄₂H₅₁N₃O₁₀Si
Molecular Weight:785.967
Hs Code.:

Synonyms:tert-butyldiphenylsilyl 4,6-di-O-benzyl-β-D-galactopyranosyl-(1->3)-2-azido-2-deoxy-β-D-galactopyranoside

Suppliers and Price of tert-butyldiphenylsilyl 4,6-di-O-benzyl-β-D-galactopyranosyl-(1->3)-2-azido-2-deoxy-β-D-galactopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyldiphenylsilyl 4,6-di-O-benzyl-β-D-galactopyranosyl-(1->3)-2-azido-2-deoxy-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyldiphenylsilyl 4,6-di-O-benzyl-β-D-galactopyranosyl-(1->3)-2-azido-2-deoxy-β-D-galactopyranoside

There total 8 articles about tert-butyldiphenylsilyl 4,6-di-O-benzyl-β-D-galactopyranosyl-(1->3)-2-azido-2-deoxy-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: [(4aR,6S,7R,8R,8aR)-8-((2R,3R,4S,5S,6R)-4-Allyloxy-6-allyloxymethyl-3,5-bis-benzyloxy-tetrahydro-pyran-2-yloxy)-7-azido-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy]-tert-butyl-diphenyl-silane

: 187157-57-9
tert-butyldiphenylsilyl 4,6-di-O-benzyl-β-D-galactopyranosyl-(1->3)-2-azido-2-deoxy-β-D-galactopyranoside

Guidance literature:: With PF4; In tetrahydrofuran; for 0.5h; Ambient temperature;
DOI:10.1016/S0008-6215(96)90116-0

Reference yield:

: tert-butyldiphenylsilyl 2-azido-4,6-O-benzylidene-2-deoxy-β-D-galactopyranoside

: 187157-57-9
tert-butyldiphenylsilyl 4,6-di-O-benzyl-β-D-galactopyranosyl-(1->3)-2-azido-2-deoxy-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1: 54 percent / 4A molecular siebes, AgOTf, SnCl₂ / 1,2-dichloro-ethane / -20 - 20 °C

2: 67 percent / LiOH, H₂O₂ / tetrahydrofuran; H₂O / 1 h / 0 °C

3: 77 percent / NaH / tetrahydrofuran / 3 h / 55 °C

4: 80 percent / 2)2>PF₄ / tetrahydrofuran / 0.5 h / Ambient temperature

With lithium hydroxide; PF4; 4A molecular siebes; dihydrogen peroxide; silver trifluoromethanesulfonate; sodium hydride; tin(ll) chloride; In tetrahydrofuran; water; 1,2-dichloro-ethane;
DOI:10.1016/S0008-6215(96)90116-0

Reference yield:

: 100-39-0
benzyl bromide

: 187157-57-9
tert-butyldiphenylsilyl 4,6-di-O-benzyl-β-D-galactopyranosyl-(1->3)-2-azido-2-deoxy-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / NaH / tetrahydrofuran / 3 h / 55 °C

2: 80 percent / 2)2>PF₄ / tetrahydrofuran / 0.5 h / Ambient temperature

With PF4; sodium hydride; In tetrahydrofuran;
DOI:10.1016/S0008-6215(96)90116-0