8-Isopropylquinoline 1-oxide

Base Information

Chemical Name:8-Isopropylquinoline 1-oxide
CAS No.:1246242-17-0
Molecular Formula:C₁₂H₁₃NO
Molecular Weight:187.241
Hs Code.:
Mol file:1246242-17-0.mol

Synonyms:8-isopropyl-quinoline-N-oxide

Suppliers and Price of 8-Isopropylquinoline 1-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
8-Isopropylquinoline N-oxide 97%
5g
$ 162.00

Sigma-Aldrich
8-Isopropylquinoline N-oxide 97%
1g
$ 45.50

AK Scientific
8-Isopropylquinoline N-oxide
5g
$ 250.00

Total 3 raw suppliers

Chemical Property of 8-Isopropylquinoline 1-oxide

Chemical Property:

Refractive Index:n20/D 1.644
Boiling Point:322.7±35.0 °C(Predicted)
PKA:0.99±0.30(Predicted)
Flash Point:>110°C
Density:1.134 g/mL at 25 °C
Storage Temp.:2-8°C

Purity/Quality:

99% ^*data from raw suppliers

8-Isopropylquinoline N-oxide 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 8-Isopropylquinoline N-oxide can be used as a reagent: In the oxidative cyclization of diynes in the presence of gold catalyst. For the preparation of pyrrolo[3,4-c]quinolin-1-ones by asymmetric alkyne oxidation of chiral N-propargyl ynamides in the presence of a copper catalyst. In the synthesis of 8-(1-methylethyl)-2-[(4-methylphenyl)sulfonyl]- quinoline by deoxygenative and selective sulfonylation with sodium p-toluenesulfinate using iodine/TBHP as a catalyst.

Technology Process of 8-Isopropylquinoline 1-oxide

There total 2 articles about 8-Isopropylquinoline 1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 6457-30-3
8-iso-propylquinoline

: 1246242-17-0
8-isopropyl-quinoline-N-oxide

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃;
DOI:10.1021/ja1072614

Reference yield:

: 643-28-7
2-isopropylaniline

: 1246242-17-0
8-isopropyl-quinoline-N-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: ferrous(II) sulfate heptahydrate; dihydroxyborane; sulfuric acid / nitrobenzene / 20 h / 120 °C / Inert atmosphere

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 6 h / 20 °C / Inert atmosphere

With ferrous(II) sulfate heptahydrate; dihydroxyborane; sulfuric acid; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; nitrobenzene;
DOI:10.1002/anie.201608181

Reference yield: 94.0%

: 75-22-9
trimethylamine-borane

: 1246242-17-0
8-isopropyl-quinoline-N-oxide

: 768-60-5
4-methoxyphenylacetylen

: 2-(trimethylamine-boranyl)-1-(4-methoxyphenyl)ethan-1-one

Guidance literature:: With (2-di-tertbutylphosphino-3,4,5,6-tetramethyl-2',4',6'-triisopropyl-1,1'-biphenyl)AuNTf₂; In dichloromethane; at 20 ℃; for 3h; regiospecific reaction;
DOI:10.1021/acscatal.8b02052