(4-Benzyloxycarbonylamino-phenyl)-(3-methyl-butyl)-piperidin-4-yl-amine

Base Information

• Chemical Name: (4-Benzyloxycarbonylamino-phenyl)-(3-methyl-butyl)-piperidin-4-yl-amine
• CAS No.: 220741-62-8
• Molecular Formula: C₂₄H₃₃N₃O₂
• Molecular Weight: 395.545

Synonyms:(4-Benzyloxycarbonylamino-phenyl)-(3-methyl-butyl)-piperidin-4-yl-amine

Chemical Property of (4-Benzyloxycarbonylamino-phenyl)-(3-methyl-butyl)-piperidin-4-yl-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-Benzyloxycarbonylamino-phenyl)-(3-methyl-butyl)-piperidin-4-yl-amine

There total 4 articles about (4-Benzyloxycarbonylamino-phenyl)-(3-methyl-butyl)-piperidin-4-yl-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-[(4-Benzyloxycarbonylamino-phenyl)-(3-methyl-butyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester (220741-61-7) → (4-Benzyloxycarbonylamino-phenyl)-(3-methyl-butyl)-piperidin-4-yl-amine (220741-62-8)

Guidance literature:

With trifluoroacetic acid; In dichloromethane;

DOI:10.1016/S0960-894X(99)00405-9

Reference yield:

N-tert-butyloxycarbonylpiperidin-4-one (79099-07-3) → (4-Benzyloxycarbonylamino-phenyl)-(3-methyl-butyl)-piperidin-4-yl-amine (220741-62-8)

Guidance literature:

Multi-step reaction with 3 steps

1: NaBH(OAc)3 / CH₂Cl₂

2: NaBH(OAc)3 / CH₂Cl₂

3: TFA / CH₂Cl₂

With sodium tris(acetoxy)borohydride; trifluoroacetic acid; In dichloromethane;

DOI:10.1016/S0960-894X(99)00405-9

Reference yield:

(4-Amino-phenyl)-carbamic acid benzyl ester (82720-42-1) → (4-Benzyloxycarbonylamino-phenyl)-(3-methyl-butyl)-piperidin-4-yl-amine (220741-62-8)

Guidance literature:

Multi-step reaction with 3 steps

1: NaBH(OAc)3 / CH₂Cl₂

2: NaBH(OAc)3 / CH₂Cl₂

3: TFA / CH₂Cl₂

With sodium tris(acetoxy)borohydride; trifluoroacetic acid; In dichloromethane;

DOI:10.1016/S0960-894X(99)00405-9

upstream raw materials:

4-[(4-Benzyloxycarbonylamino-phenyl)-(3-methyl-butyl)-amino]-piperidine-1-carboxylic acid tert-butyl ester

N-tert-butyloxycarbonylpiperidin-4-one

(4-Amino-phenyl)-carbamic acid benzyl ester

4-(4-benzyloxycarbonylamino-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester

Downstream raw materials:

(S)-Azepane-1-carboxylic acid (1-{4-[(4-amino-phenyl)-(3-methyl-butyl)-amino]-piperidine-1-carbonyl}-3-methyl-butyl)-amide

(S)-{4-[(1-{2-[(Azepane-1-carbonyl)-amino]-4-methyl-pentanoyl}-piperidin-4-yl)-(3-methyl-butyl)-amino]-phenyl}-carbamic acid benzyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 220741-62-8 (4-Benzyloxycarbonylamino-phenyl)-(3-methyl-butyl)-piperidin-4-yl-amine

Send

Send

Metric Ton KG G Pound L ML

Send

Send