4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tri-O-benzyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1-thio-β-D-glucopyranoside

Base Information

• Chemical Name: 4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tri-O-benzyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1-thio-β-D-glucopyranoside
• CAS No.: 1095998-58-5
• Molecular Formula: C₆₉H₆₀N₂O₁₄S₂
• Molecular Weight: 1205.37
• Mol file: 1095998-58-5.mol

Synonyms:4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tri-O-benzyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1-thio-β-D-glucopyranoside

Chemical Property of 4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tri-O-benzyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1-thio-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tri-O-benzyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1-thio-β-D-glucopyranoside

There total 5 articles about 4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tri-O-benzyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1-thio-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-glucopyranoside (105376-04-3,138661-53-7,113214-71-4) + 4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tetra-O-benzyl-1-thio-β-D-glucopyranoside (1095998-39-2) → 4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tri-O-benzyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1-thio-β-D-glucopyranoside (1095998-58-5)

Guidance literature:

4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tetra-O-benzyl-1-thio-β-D-glucopyranoside; With palladium(II) bromide; In 1,2-dichloro-ethane; at 20 ℃; Molecular sieve;

ethyl 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-glucopyranoside; With methyl trifluoromethanesulfonate; In 1,2-dichloro-ethane; for 4h; Molecular sieve; Inert atmosphere;

With sodium cyanide; In acetone; at 20 ℃; for 16h;

DOI:10.1039/b810569c

Reference yield:

4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tetra-O-benzyl-1-thio-β-D-glucopyranoside (1095998-39-2) + 2,3,4,6-tetra-O-benzoyl-D-glucopyranosyl trichloroacetimidate (149707-75-5) → 4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tri-O-benzyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1-thio-β-D-glucopyranoside (1095998-58-5)

Guidance literature:

4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tetra-O-benzyl-1-thio-β-D-glucopyranoside; With palladium(II) bromide; In 1,2-dichloro-ethane; at 20 ℃; Molecular sieve;

2,3,4,6-tetra-O-benzoyl-D-glucopyranosyl trichloroacetimidate; With trimethylsilyl trifluoromethanesulfonate; In 1,2-dichloro-ethane; for 0.166667h; Molecular sieve; Inert atmosphere;

With sodium cyanide; In acetone; at 20 ℃; for 16h;

DOI:10.1039/b810569c

Reference yield:

4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tetra-O-benzyl-1-thio-β-D-glucopyranoside (1095998-39-2) + 4-(pyridine-2-yl)-thiazole-2-yl 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-glucopyranoside (1095998-28-9) → 4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tri-O-benzyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1-thio-β-D-glucopyranoside (1095998-58-5)

Guidance literature:

4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tetra-O-benzyl-1-thio-β-D-glucopyranoside; With palladium(II) bromide; In 1,2-dichloro-ethane; at 20 ℃; Molecular sieve;

4-(pyridine-2-yl)-thiazole-2-yl 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-glucopyranoside; With silver trifluoromethanesulfonate; In 1,2-dichloro-ethane; for 24h; Molecular sieve; Inert atmosphere;

With sodium cyanide; In acetone; at 20 ℃; for 16h;

DOI:10.1039/b810569c

upstream raw materials:

4-(pyridin-2-yl)thiazole-2-yl 2,4,6-tetra-O-benzyl-1-thio-β-D-glucopyranoside

4-(pyridine-2-yl)-thiazole-2-yl 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-glucopyranoside

ethyl 2,3,4,6-tetra-O-benzoyl-1-thio-β-D-glucopyranoside

2,3,4,6-tetra-O-benzoyl-D-glucopyranosyl trichloroacetimidate