<<3-chloro-4-(difluoromethoxy)phenyl>amino>methylenepropanedioic acid diethyl ester

Base Information

Chemical Name:<<3-chloro-4-(difluoromethoxy)phenyl>amino>methylenepropanedioic acid diethyl ester
CAS No.:115712-80-6
Molecular Formula:C₁₅H₁₆ClF₂NO₅
Molecular Weight:363.746
Hs Code.:

Synonyms:<<3-chloro-4-(difluoromethoxy)phenyl>amino>methylenepropanedioic acid diethyl ester

Suppliers and Price of <<3-chloro-4-(difluoromethoxy)phenyl>amino>methylenepropanedioic acid diethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of <<3-chloro-4-(difluoromethoxy)phenyl>amino>methylenepropanedioic acid diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of <<3-chloro-4-(difluoromethoxy)phenyl>amino>methylenepropanedioic acid diethyl ester

There total 3 articles about <<3-chloro-4-(difluoromethoxy)phenyl>amino>methylenepropanedioic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 87-13-8
diethyl 2-ethoxymethylenemalonate

: 115700-24-8
3-Chloro-4-difluoromethoxy-phenylamine; hydrochloride

: 115712-80-6
<<3-chloro-4-(difluoromethoxy)phenyl>amino>methylenepropanedioic acid diethyl ester

Guidance literature:: With triethylamine; at 120 - 130 ℃; for 16h;
DOI:10.1002/jps.2600770521

Reference yield:

: 619-08-9
2-chloro-4-nitrophenol

: 115712-80-6
<<3-chloro-4-(difluoromethoxy)phenyl>amino>methylenepropanedioic acid diethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / aq. NaOH / tetrahydrofuran / 18 h / 40 - 45 °C

2: 95 percent / aq. HCl / Pd/C / ethanol / 0.75 h / 2585.7 Torr

3: 87 percent / Et₃N / 16 h / 120 - 130 °C

With hydrogenchloride; sodium hydroxide; triethylamine; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1002/jps.2600770521

Reference yield:

: 40319-63-9
2-chloro-1-(difluoromethoxy)-4-nitrobenzene

: 115712-80-6
<<3-chloro-4-(difluoromethoxy)phenyl>amino>methylenepropanedioic acid diethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / aq. HCl / Pd/C / ethanol / 0.75 h / 2585.7 Torr

2: 87 percent / Et₃N / 16 h / 120 - 130 °C

With hydrogenchloride; triethylamine; palladium on activated charcoal; In ethanol;
DOI:10.1002/jps.2600770521