C₁₉H₁₂Cl₂N₂

Base Information

• Chemical Name: C₁₉H₁₂Cl₂N₂
• CAS No.: 1228267-20-6
• Molecular Formula: C₁₉H₁₂Cl₂N₂
• Molecular Weight: 339.224
• Mol file: 1228267-20-6.mol

Synonyms:C₁₉H₁₂Cl₂N₂

Chemical Property of C₁₉H₁₂Cl₂N₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₁₉H₁₂Cl₂N₂

There total 3 articles about C₁₉H₁₂Cl₂N₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

2'-chloro[1,1'-biphenyl]-2-carboxaldehyde (223575-76-6) + 5-Chloro-2-azidoaniline (75458-14-9) → C19H12Cl2N2 (1228267-20-6)

Guidance literature:

With acetic acid; In ethanol; for 21h; Reflux;

Reference yield:

2-bromo-1-chlorobenzene (694-80-4) → C19H12Cl2N2 (1228267-20-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / water; tetrahydrofuran / 5 h / Reflux

2: acetic acid / ethanol / 21 h / Reflux

With potassium carbonate; acetic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; ethanol; water; 1: Suzuki Coupling;

Reference yield:

2-formylbenzene boronic acid (40138-16-7) → C19H12Cl2N2 (1228267-20-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / water; tetrahydrofuran / 5 h / Reflux

2: acetic acid / ethanol / 21 h / Reflux

With potassium carbonate; acetic acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; ethanol; water; 1: Suzuki Coupling;

upstream raw materials:

2-bromo-1-chlorobenzene

2-formylbenzene boronic acid

2'-chloro[1,1'-biphenyl]-2-carboxaldehyde

5-Chloro-2-azidoaniline

Refernces