1-[N-(4-methoxy-phenyl)-benzimidoyl]-3,5-dimethyl-1H-pyrazole

Base Information

• Chemical Name: 1-[N-(4-methoxy-phenyl)-benzimidoyl]-3,5-dimethyl-1H-pyrazole
• CAS No.: 36640-74-1
• Molecular Formula: C₁₉H₁₉N₃O
• Molecular Weight: 305.379
• Mol file: 36640-74-1.mol

Synonyms:1-[N-(4-methoxy-phenyl)-benzimidoyl]-3,5-dimethyl-1H-pyrazole

Chemical Property of 1-[N-(4-methoxy-phenyl)-benzimidoyl]-3,5-dimethyl-1H-pyrazole

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 1-[N-(4-methoxy-phenyl)-benzimidoyl]-3,5-dimethyl-1H-pyrazole

There total 2 articles about 1-[N-(4-methoxy-phenyl)-benzimidoyl]-3,5-dimethyl-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.6%

3,5-dimethyl-1H-pyrazole (67-51-6) + N-(4-methoxyphenyl)benzimidoyl chloride (34918-74-6) → 1-[N-(4-methoxy-phenyl)-benzimidoyl]-3,5-dimethyl-1H-pyrazole (36640-74-1)

Guidance literature:

With triethylamine; In acetonitrile; for 5h; Heating;

DOI:10.1021/jm00144a031

Reference yield:

→ 1-[N-(4-methoxy-phenyl)-benzimidoyl]-3,5-dimethyl-1H-pyrazole (36640-74-1)

Guidance literature:

3,5-Dimethylpyrazol, N-(p-anisyl)-benzimidsaeurechlorid;

Reference yield: 98.0%

nickel(II) bromide dimethoxyethane (28923-39-9) + 1-[N-(4-methoxy-phenyl)-benzimidoyl]-3,5-dimethyl-1H-pyrazole (36640-74-1) → bis-2-(C3HN2Me2-3,5)(C(Ph)=N(4-CH3OC6H4))NiBr2 (1107646-49-0)

Guidance literature:

In dichloromethane; (N2); 1 equiv. of (DME)2NiBr2 was added to soln. of 2 equiv. of pyrazolylimine in CH2Cl2, stirred at room temp. for 18 h; concd., pptd. with hexane, washed with hexane, dried in vac., elem. anal.;

DOI:10.1016/j.ica.2008.03.068

upstream raw materials:

3,5-dimethyl-1H-pyrazole

N-(4-methoxyphenyl)benzimidoyl chloride

Downstream raw materials:

bis-2-(C₃HN₂Me₂-3,5)(C(Ph)=N(4-CH₃OC₆H₄))NiBr₂