5-Morpholino-1H-pyrazol-3-amine

Base Information

Chemical Name:5-Morpholino-1H-pyrazol-3-amine
CAS No.:756814-98-9
Molecular Formula:C7H12 N4 O
Molecular Weight:168.2
Hs Code.:2934999090
DSSTox Substance ID:DTXSID10398985
Wikidata:Q82201268
Mol file:756814-98-9.mol

Synonyms:5-Morpholino-1H-pyrazol-3-amine;756814-98-9;3-morpholin-4-yl-1H-pyrazol-5-amine;3-(Morpholin-4-yl)-1h-pyrazol-5-amine;5-morpholin-4-yl-2h-pyrazol-3-ylamine;3-morpholino-1h-pyrazol-5-amine;SCHEMBL922909;DTXSID10398985;AMY28921;MFCD03414619;AKOS006278899;AS-40232;CS-0366006;FT-0689736;5-(MORPHOLIN-4-YL)-1H-PYRAZOL-3-AMINE;A934298

Suppliers and Price of 5-Morpholino-1H-pyrazol-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Morpholin-4-yl-2H-pyrazol-3-ylamine
2.5mg
$ 45.00

Crysdot
5-Morpholino-1H-pyrazol-3-amine 95+%
1g
$ 432.00

Chemenu
5-morpholino-1H-pyrazol-3-amine 95%
1g
$ 408.00

American Custom Chemicals Corporation
5-MORPHOLINO-1H-PYRAZOL-3-AMINE 95.00%
5MG
$ 498.08

Alichem
5-Morpholino-1H-pyrazol-3-amine
5g
$ 2402.99

Alichem
5-Morpholino-1H-pyrazol-3-amine
1g
$ 1024.08

Alichem
5-Morpholino-1H-pyrazol-3-amine
250mg
$ 410.04

Total 6 raw suppliers

Chemical Property of 5-Morpholino-1H-pyrazol-3-amine

Chemical Property:

Boiling Point:481.2±45.0 °C(Predicted)
PKA:17.19±0.10(Predicted)
PSA：67.17000
Density:1.328±0.06 g/cm3(Predicted)
LogP:0.47470
Storage Temp.:2-8°C(protect from light)
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:168.10111102
Heavy Atom Count:12
Complexity:148

Purity/Quality:

99% ^*data from raw suppliers

5-Morpholin-4-yl-2H-pyrazol-3-ylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=NNC(=C2)N

Technology Process of 5-Morpholino-1H-pyrazol-3-amine

There total 1 articles about 5-Morpholino-1H-pyrazol-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 537039-14-8
C₈H₁₂N₂OS

: 756814-98-9
C₇H₁₂N₄O

Guidance literature:: With hydrazine; In ethanol; for 18h; Reflux;
DOI:10.1016/j.bmcl.2009.10.074

Reference yield: 80.0%

: 950738-59-7
N-[3-(3-dimethylaminoacryloyl)phenyl]-3-trifluoromethylbenzamide

: 756814-98-9
C₇H₁₂N₄O

: N-(3-(2-morpholinopyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3-(trifluoromethyl)benzamide

Guidance literature:: With acetic acid; at 80 ℃; for 18h;
DOI:10.1016/j.bmcl.2009.10.074

Reference yield:

: 756814-98-9
C₇H₁₂N₄O

: 1269515-96-9
2,6-difluoro-N-(2-morpholinopyrazolo[1,5-a]pyrimidin-6-yl)-3-(propylsulfonamido)benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid / 16 h / 22 - 40 °C

2: palladium 10% on activated carbon; hydrogen / ethanol / 4 h

3: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 15 h / 22 °C

With palladium 10% on activated carbon; hydrogen; benzotriazol-1-ol; acetic acid; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2011.11.092