Diethyl 8-isocyano-2,2,14,14-tetramethyl-8-tosylpentadecanedioate

Base Information

Chemical Name:Diethyl 8-isocyano-2,2,14,14-tetramethyl-8-tosylpentadecanedioate
CAS No.:738606-44-5
Molecular Formula:C₃₁H₄₉NO₆S
Molecular Weight:563.799
Hs Code.:
European Community (EC) Number:879-454-4

Synonyms:Diethyl 8-isocyano-2,2,14,14-tetramethyl-8-tosylpentadecanedioate;738606-44-5;diethyl 8-isocyano-2,2,14,14-tetramethyl-8-(4-methylphenyl)sulfonylpentadecanedioate;SCHEMBL186525;UZZLDIFAUXUEAY-UHFFFAOYSA-N;CS-0105212;8-isocyano-2,2,14,14-tetramethyl-8-(toluene-4-sulfonyl)-pentadecanedioic acid diethyl ester;pentadecanedioic acid,8-isocyano-2,2,14,14-tetramethyl-8-((4-methylphenyl)sulfonyl)-,1,15-diethyl ester

Suppliers and Price of Diethyl 8-isocyano-2,2,14,14-tetramethyl-8-tosylpentadecanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 9 raw suppliers

Chemical Property of Diethyl 8-isocyano-2,2,14,14-tetramethyl-8-tosylpentadecanedioate

Chemical Property:

XLogP3:7.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:20
Exact Mass:563.32805946
Heavy Atom Count:39
Complexity:877

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C(C)(C)CCCCCC(CCCCCC(C)(C)C(=O)OCC)([N+]#[C-])S(=O)(=O)C1=CC=C(C=C1)C

Technology Process of Diethyl 8-isocyano-2,2,14,14-tetramethyl-8-tosylpentadecanedioate

There total 5 articles about Diethyl 8-isocyano-2,2,14,14-tetramethyl-8-tosylpentadecanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 38622-91-2,36635-61-7
[(p-methylphenyl)sulfonylmethyl]isonitrile

: 123469-92-1
ethyl-2,2-dimethyl-7-bromoheptanoate

: 738606-44-5
8-isocyano-2,2,14,14-tetramethyl-8-(toluene-4-sulfonyl)-pentadecanedioic acid diethyl ester

Guidance literature:: With tetra-(n-butyl)ammonium iodide; sodium hydride; In dimethyl sulfoxide; at 20 ℃; for 20h;
DOI:10.1021/jm040006p

Reference yield:

: 111-24-0
1,5-dibromo-pentane

: 738606-44-5
8-isocyano-2,2,14,14-tetramethyl-8-(toluene-4-sulfonyl)-pentadecanedioic acid diethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 44 percent / LDA / tetrahydrofuran / -78 - 20 °C

2: NaH; NBu₄I / dimethylsulfoxide / 20 h / 20 °C

With tetra-(n-butyl)ammonium iodide; sodium hydride; lithium diisopropyl amide; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1021/jm040006p

Reference yield:

: 97-62-1
Ethyl isobutyrate

: 738606-44-5
8-isocyano-2,2,14,14-tetramethyl-8-(toluene-4-sulfonyl)-pentadecanedioic acid diethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 44 percent / LDA / tetrahydrofuran / -78 - 20 °C

2: NaH; NBu₄I / dimethylsulfoxide / 20 h / 20 °C

With tetra-(n-butyl)ammonium iodide; sodium hydride; lithium diisopropyl amide; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1021/jm040006p