(R)-2-ChloroMandelic Acid Ethyl Ester

Base Information

Chemical Name:(R)-2-ChloroMandelic Acid Ethyl Ester
CAS No.:421545-87-1
Molecular Formula:C₁₀H₁₁ClO₃
Molecular Weight:214.649
Hs Code.:
Mol file:421545-87-1.mol

Synonyms:ethyl 2-(2-chlorophenyl)-2-hydroxyacetate

Suppliers and Price of (R)-2-ChloroMandelic Acid Ethyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-2-ChloromandelicAcidEthylEster
1g
$ 970.00

Medical Isotopes, Inc.
(R)-2-ChloromandelicAcidEthylEster
100 mg
$ 610.00

Total 2 raw suppliers

Chemical Property of (R)-2-ChloroMandelic Acid Ethyl Ester

Chemical Property:

Solubility.:Dichloromethane, Ethyl Acetate

Purity/Quality:

99% ^*data from raw suppliers

(R)-2-ChloromandelicAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses (R)-2-Chloromandelic Acid Ethyl Ester is a reactant used in the preparation of (R,S)-Et 2-chloromandelate, an important intermediate for the synthesis of Clopidogrel. (R)-2-Chloromandelic Acid Ethyl Ester is used in the preparation of chiral alcohols.

Technology Process of (R)-2-ChloroMandelic Acid Ethyl Ester

There total 7 articles about (R)-2-ChloroMandelic Acid Ethyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 62123-75-5
ethyl 2-(2-chlorophenyl)-2-oxoacetate

: 421545-87-1,871836-58-7
ethyl 2-(2-chlorophenyl)-2-hydroxyacetate

Guidance literature:: With cyclohexanone monooxygenase mutant L₁₄₃F from Acinetobacter sp. NCIMB 9871 in Escherichia coli whole-cell culture medium; In acetonitrile; at 20 ℃; enantioselective reaction; Catalytic behavior; Inert atmosphere; Microbiological reaction; Enzymatic reaction;
DOI:10.1002/anie.201907606

Reference yield:

: 13511-30-3,871836-58-7
ethyl 2-(2-chlorophenyl)-2-hydroxyacetate

: 10421-85-9,52923-23-6,52950-18-2,52950-19-3
(S)-2-chloromandelic acid

: 421545-87-1,871836-58-7
ethyl 2-(2-chlorophenyl)-2-hydroxyacetate

Guidance literature:: With potassium dihydrogenphosphate; phosphoric acid; water; CAL A lipase; at 30 ℃; for 42h; pH=7.0; Product distribution / selectivity; buffer solution; Enzymatic reaction;

Reference yield:

: 62123-75-5
ethyl 2-(2-chlorophenyl)-2-oxoacetate

: 871836-58-7
ethyl 2-chloromandelate

: 421545-87-1,871836-58-7
ethyl 2-(2-chlorophenyl)-2-hydroxyacetate

Guidance literature:: With cerium(III) chloride; hydrogen; dichloro(benzene)ruthenium(II) dimer; (2,2,2',2'-tetramethyl[4,4'-bibenzo[d][1,3]dioxole]-5,5'-diyl)bis(diphenylphosphine); In ethanol; at 70 ℃; for 20h; under 38000 Torr; Title compound not separated from byproducts;
DOI:10.1021/ol052212c