potassium (1-(N,N-diisopropylcarbamoyl)-3-phenylpropyl)trifluoroboranuide

Base Information

• Chemical Name: potassium (1-(N,N-diisopropylcarbamoyl)-3-phenylpropyl)trifluoroboranuide
• CAS No.: 1402010-36-9
• Molecular Formula: C₁₆H₂₄BF₃NO₂*K
• Molecular Weight: 369.277
• Mol file: 1402010-36-9.mol

Synonyms:potassium (1-(N,N-diisopropylcarbamoyl)-3-phenylpropyl)trifluoroboranuide

Chemical Property of potassium (1-(N,N-diisopropylcarbamoyl)-3-phenylpropyl)trifluoroboranuide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of potassium (1-(N,N-diisopropylcarbamoyl)-3-phenylpropyl)trifluoroboranuide

There total 5 articles about potassium (1-(N,N-diisopropylcarbamoyl)-3-phenylpropyl)trifluoroboranuide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

N,N-diisopropylcarbamoyl chloride (19009-39-3) + potassium (1-hydroxy-3-phenylpropyl)trifluoroboranuide (1402010-12-1) → potassium (1-(N,N-diisopropylcarbamoyl)-3-phenylpropyl)trifluoroboranuide (1402010-36-9)

Guidance literature:

With potassium hydride; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/ja307861n

Reference yield:

C15H23BO3 → potassium (1-(N,N-diisopropylcarbamoyl)-3-phenylpropyl)trifluoroboranuide (1402010-36-9)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol; water / 0 - 20 °C

2: potassium hydride / tetrahydrofuran / 20 °C

With potassium hydride; In tetrahydrofuran; methanol; water;

DOI:10.1021/ja307861n

Reference yield:

3-phenylpropyl N,N-diisopropylcarbamate (218601-55-9) → potassium (1-(N,N-diisopropylcarbamoyl)-3-phenylpropyl)trifluoroboranuide (1402010-36-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium / 5 h / -78 °C

1.2: 1 h

2.1: water

With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In water;

DOI:10.1021/ja307861n

upstream raw materials:

methanol

N,N-diisopropylcarbamoyl chloride

potassium (1-hydroxy-3-phenylpropyl)trifluoroboranuide

3-phenylpropyl N,N-diisopropylcarbamate