C₁₆H₁₂Cl₂O₃

Base Information

• Chemical Name: C₁₆H₁₂Cl₂O₃
• CAS No.: 1398523-50-6
• Molecular Formula: C₁₆H₁₂Cl₂O₃
• Molecular Weight: 323.175
• Mol file: 1398523-50-6.mol

Synonyms:C₁₆H₁₂Cl₂O₃

Chemical Property of C₁₆H₁₂Cl₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₁₆H₁₂Cl₂O₃

There total 1 articles about C₁₆H₁₂Cl₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(4-methoxyphenyl)ethanone (100-06-1) + 3,5-dichlorosalicyclaldehyde (90-60-8) → C16H12Cl2O3 (1398523-50-6)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 0 - 20 ℃;

DOI:10.1016/j.bmc.2012.08.020

Reference yield: 92.0%

C16H12Cl2O3 (1398523-50-6) + malononitrile (109-77-3) → C19H14Cl2N2O3

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 40 - 45 ℃;

Reference yield: 79.0%

4-hydroxy[1]benzopyran-2-one (1076-38-6,92395-12-5) + C16H12Cl2O3 (1398523-50-6) → C25H16Cl2O5

Guidance literature:

In toluene; stereoselective reaction; Reflux; Sealed tube;

DOI:10.1021/jo400081q

upstream raw materials:

1-(4-methoxyphenyl)ethanone

3,5-dichlorosalicyclaldehyde

Downstream raw materials:

C₁₈H₁₆Cl₂N₂O₃

C₁₆H₁₄Cl₂N₂O₂