ethyl 2-(6-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-erythro-hex-2-enopyranosyl)-2,2-difluoroacetate

Base Information

• Chemical Name: ethyl 2-(6-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-erythro-hex-2-enopyranosyl)-2,2-difluoroacetate
• CAS No.: 1014698-47-5
• Molecular Formula: C₂₆H₃₂F₂O₅Si
• Molecular Weight: 490.619
• Mol file: 1014698-47-5.mol

Synonyms:ethyl 2-(6-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-erythro-hex-2-enopyranosyl)-2,2-difluoroacetate

Chemical Property of ethyl 2-(6-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-erythro-hex-2-enopyranosyl)-2,2-difluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 2-(6-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-erythro-hex-2-enopyranosyl)-2,2-difluoroacetate

There total 1 articles about ethyl 2-(6-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-erythro-hex-2-enopyranosyl)-2,2-difluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H14F2O5 (1030595-58-4) + tert-butylchlorodiphenylsilane (58479-61-1) → ethyl 2-(6-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-erythro-hex-2-enopyranosyl)-2,2-difluoroacetate (1014698-47-5) + ethyl 2-(6-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranosyl)-2,2-difluoroacetate (1014698-42-0)

Guidance literature:

With dmap; triethylamine; In dichloromethane; for 24h;

DOI:10.1021/jo702466h

Reference yield: 86.0%

ethyl 2-(6-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-erythro-hex-2-enopyranosyl)-2,2-difluoroacetate (1014698-47-5) → C26H32F2O6Si (1149347-37-4)

Guidance literature:

With Oxone; ethylenediaminetetraacetic acid; 1,1,1-trifluoro-2-propanone; sodium hydrogencarbonate; In water; acetonitrile; at 0 ℃;

DOI:10.1016/j.tetlet.2009.01.155

Reference yield: 68.0%

ethyl 2-(6-O-(tert-butyldiphenylsilyl)-2,3-dideoxy-β-D-erythro-hex-2-enopyranosyl)-2,2-difluoroacetate (1014698-47-5) → ethyl 2-(6-O-(tert-butyldiphenylsilyl)-β-D-allopyranosyl)-2,2-difluoroacetate (1014698-48-6)

Guidance literature:

With osmium(VIII) oxide; N-methyl-2-indolinone; In dichloromethane; water;

DOI:10.1021/jo702466h

upstream raw materials:

C₁₀H₁₄F₂O₅

tert-butylchlorodiphenylsilane

Downstream raw materials:

ethyl 2-(6-O-(tert-butyldiphenylsilyl)-β-D-allopyranosyl)-2,2-difluoroacetate

C₂₆H₃₂F₂O₆Si