S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-methyl-N-cyano sulfoximide

Base Information

Chemical Name:S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-methyl-N-cyano sulfoximide
CAS No.:1147095-68-8
Molecular Formula:C₂₁H₁₅Cl₂N₅O₃S
Molecular Weight:488.354
Hs Code.:

Synonyms:S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-methyl-N-cyano sulfoximide

Suppliers and Price of S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-methyl-N-cyano sulfoximide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-methyl-N-cyano sulfoximide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-methyl-N-cyano sulfoximide

There total 10 articles about S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-methyl-N-cyano sulfoximide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 506-68-3
bromocyane

: 1147095-59-7,1147096-64-7
S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-methyl sulfoximide

: 1147095-68-8
S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-methyl-N-cyano sulfoximide

Guidance literature:: With dmap; In dichloromethane; at 25 - 30 ℃; for 6h; Inert atmosphere;
DOI:10.1016/j.ejmech.2012.10.005

Reference yield:

: 1147096-51-2
methyl 4-[imino(methyl)oxo-λ⁶-sulfanyl]benzoate

: 1147095-68-8
S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-methyl-N-cyano sulfoximide

Guidance literature:: Multi-step reaction with 6 steps

1.1: pyridine / dichloromethane / 3 h / 15 - 30 °C / Inert atmosphere

2.1: sodium hydroxide; water / tetrahydrofuran / 3 h / 25 - 30 °C

2.2: 0 °C

3.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 3 h / 10 - 30 °C / Inert atmosphere

4.1: tetrahydrofuran / 12 h / 10 - 30 °C / Inert atmosphere

5.1: sulfuric acid / 0 - 5 °C

6.1: dmap / dichloromethane / 18 h / 25 - 30 °C

With pyridine; dmap; oxalyl dichloride; sulfuric acid; water; sodium hydroxide; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;

Reference yield:

: 114129-35-0
methyl 4-(methylsulfinyl)benzoate

: 1147095-68-8
S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-methyl-N-cyano sulfoximide

Guidance literature:: Multi-step reaction with 7 steps

1.1: sodium azide; sulfuric acid / chloroform / 15 h / -20 - 50 °C / Inert atmosphere

2.1: pyridine / dichloromethane / 3 h / 15 - 30 °C / Inert atmosphere

3.1: sodium hydroxide; water / tetrahydrofuran / 3 h / 25 - 30 °C

3.2: 0 °C

4.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 3 h / 10 - 30 °C / Inert atmosphere

5.1: tetrahydrofuran / 12 h / 10 - 30 °C / Inert atmosphere

6.1: sulfuric acid / 0 - 5 °C

7.1: dmap / dichloromethane / 18 h / 25 - 30 °C

With pyridine; dmap; sodium azide; oxalyl dichloride; sulfuric acid; water; sodium hydroxide; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane; chloroform;