(R)-3-[2-(2-t-butoxycarbonylamino-5-trifluoromethoxybenzamide)acetamide]-1-(6-methylindol-3-ylmethyl)pyprrolidine

Base Information

Chemical Name:(R)-3-[2-(2-t-butoxycarbonylamino-5-trifluoromethoxybenzamide)acetamide]-1-(6-methylindol-3-ylmethyl)pyprrolidine
CAS No.:850140-82-8
Molecular Formula:C₂₉H₃₄F₃N₅O₅
Molecular Weight:589.615
Hs Code.:

Synonyms:(R)-3-[2-(2-t-butoxycarbonylamino-5-trifluoromethoxybenzamide)acetamide]-1-(6-methylindol-3-ylmethyl)pyprrolidine

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Chemical Property of (R)-3-[2-(2-t-butoxycarbonylamino-5-trifluoromethoxybenzamide)acetamide]-1-(6-methylindol-3-ylmethyl)pyprrolidine

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Technology Process of (R)-3-[2-(2-t-butoxycarbonylamino-5-trifluoromethoxybenzamide)acetamide]-1-(6-methylindol-3-ylmethyl)pyprrolidine

There total 3 articles about (R)-3-[2-(2-t-butoxycarbonylamino-5-trifluoromethoxybenzamide)acetamide]-1-(6-methylindol-3-ylmethyl)pyprrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 226249-18-9
(R)-3-[N-[2-(tert-butoxycarbonylamino)-5-(trifluoromethoxyl)benzoyl]glycyl]aminopyrrolidine

: 6-methylgramine

: 850140-82-8
(R)-3-[2-(2-t-butoxycarbonylamino-5-trifluoromethoxybenzamide)acetamide]-1-(6-methylindol-3-ylmethyl)pyprrolidine

Guidance literature:: In isopropyl alcohol; at 95 ℃;

Reference yield:

: 604765-67-5
2-(2-t-butoxycarbonylamino-5-trifluoromethoxybenzamide)acetic acid

: (R)-3-amino-1-(6-methylindol-3-ylmethyl)pyprrolidine trihydrochloride

: 850140-82-8
(R)-3-[2-(2-t-butoxycarbonylamino-5-trifluoromethoxybenzamide)acetamide]-1-(6-methylindol-3-ylmethyl)pyprrolidine

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; at 45 ℃; for 20h;

Reference yield:

: 604765-67-5
2-(2-t-butoxycarbonylamino-5-trifluoromethoxybenzamide)acetic acid

: (R)-3-amino-1-(6-methylindol-3-ylmethyl)pyprrolidine

: 850140-82-8
(R)-3-[2-(2-t-butoxycarbonylamino-5-trifluoromethoxybenzamide)acetamide]-1-(6-methylindol-3-ylmethyl)pyprrolidine

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; at 45 ℃; for 20h;