(S)-(1-(6-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)carbamate tert-butyl ester

Base Information

Chemical Name:(S)-(1-(6-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)carbamate tert-butyl ester
CAS No.:1615253-60-5
Molecular Formula:C₂₁H₂₂FN₃O₃
Molecular Weight:383.422
Hs Code.:

Synonyms:(S)-(1-(6-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)carbamate tert-butyl ester

Suppliers and Price of (S)-(1-(6-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)carbamate tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-(1-(6-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)carbamate tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-(1-(6-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)carbamate tert-butyl ester

There total 10 articles about (S)-(1-(6-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)carbamate tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (S)-(1-((4-fluoro-2-(phenylcarbamoyl)phenyl)amino)-1-oxopropan-2-yl )carbamate tert-butyl ester

: 1615253-60-5
(S)-(1-(6-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)carbamate tert-butyl ester

Guidance literature:: With dmap; N-ethyl-N,N-diisopropylamine; bovine serum albumin; In acetonitrile; at 80 ℃; for 5h; Inert atmosphere; Enzymatic reaction;

Reference yield:

: (S)-tert-butyl (1-(6-fluoro-4-oxo-4H-benzo[d][1,3]oxazin-2-yl)ethyl)carbamate

: 62-53-3
aniline

: 1615253-60-5
(S)-(1-(6-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)carbamate tert-butyl ester

Guidance literature:: at 0.4 - 55 ℃; Large scale;

Reference yield:

: 320-98-9
5-fluoro-2-nitrobenzoic acid

: 1615253-60-5
(S)-(1-(6-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)carbamate tert-butyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: thionyl chloride; N,N-dimethyl-formamide / tetrahydrofuran / 5 h / 60 °C / Inert atmosphere

2: triethylamine / tetrahydrofuran / 0 °C

3: iron; ammonium formate / ethanol; water / 90 °C

4: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane / 0 - 45 °C / Inert atmosphere

5: N-ethyl-N,N-diisopropylamine; dmap; bovine serum albumin / acetonitrile / 5 h / 80 °C / Inert atmosphere; Enzymatic reaction

With dmap; thionyl chloride; ammonium formate; iron; triethylamine; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; HATU; bovine serum albumin; In tetrahydrofuran; ethanol; dichloromethane; water; acetonitrile;